1353723-35-9

Upstream product

• 1353722-98-1 (E)-1-acetoxy-5-carbamoyl-3-methylpent-2-ene 
• 1353723-00-8 (E)-6-amino-3-methylhex-2-en-1-ol 
• 1353722-65-2 (E)-6-((tert-butoxycarbonyl)amino)-3-methylhex-2-en-1-ol 
• 35334-60-2 (E)-6-acetoxy-4-methyl-4-hexenal 
• 27872-60-2 (E)-1-acetoxy-5-carboxy-3-methylpent-2-ene 

Relevant academic research and scientific papers

Enantioselective synthesis of pyrrolidine-, Piperidine-, and azepane-type N -heterocycles with α-alkenyl substitution: The CpRu-catalyzed dehydrative intramolecular N -allylation approach

A cationic CpRu complex of chiral picolinic acid derivatives [(R)- or (S)-Cl-Naph-PyCOOCH2CH=CH2] catalyzes asymmetric intramolecular dehydrative N-allylation of N-substituted ω-amino- and -aminocarbonyl allylic alcohols with a substrate/catalyst ratio of up to 2000 to give α-alkenyl pyrrolidine-, piperidine-, and azepane-type N-heterocycles with an enantiomer ratio of up to >99:1. The wide range of applicable N-substitutions, including Boc, Cbz, Ac, Bz, acryloyl, crotonoyl, formyl, and Ts, significantly facilitates further manipulation toward natural product synthesis.