1353754-63-8

Basic information

• Product Name: (6S)-2-nitro-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazin-6-yl [4'-(trifluoromethoxy)biphenyl-4-yl]carbamate
• CAS NO: 1353754-63-8
• Molecular Weight: 464.358
• Mol File: 1353754-63-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (6S)-2-nitro-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazin-6-yl [4'-(trifluoromethoxy)biphenyl-4-yl]carbamate(CAS DataBase Reference)
• NIST Chemistry Reference: (6S)-2-nitro-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazin-6-yl [4'-(trifluoromethoxy)biphenyl-4-yl]carbamate(1353754-63-8)
• EPA Substance Registry System: (6S)-2-nitro-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazin-6-yl [4'-(trifluoromethoxy)biphenyl-4-yl]carbamate(1353754-63-8)

Safety Data

• Hazardous Substances Data: 1353754-63-8(Hazardous Substances Data)

Upstream product

• 2493-02-9 4-bromophenyl isocyanate 
• 187235-49-0 (6S)-2-nitro-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazin-6-yl (4-bromophenyl)carbamate 
• 139301-27-2 4-trifluoromethoxyphenylboronic acid 
• 187235-08-1 (S)‐2‐nitro‐6,7‐dihydro‐5H‐imidazo[2,1‐b][1,3]oxazin‐6‐ol 

Relevant articles and documents

Structure-activity relationships for amide-, carbamate-, and urea-linked analogues of the tuberculosis drug (6S)-2-nitro-6-{[4-(trifluoromethoxy)benzyl] oxy}-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine (PA-824)

Analogues of clinical tuberculosis drug (6S)-2-nitro-6-{[4- (trifluoromethoxy)benzyl]oxy}-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine (PA-824), in which the OCH2 linkage was replaced with amide, carbamate, and urea functionality, were investigate