1353757-75-1Relevant academic research and scientific papers
A unique and simple preparative method for α-aryl-pipecolinic acid esters via base-induced sommelet-hauser rearrangement
Tayama, Eiji,Sato, Ryota,Ito, Motoshi,Iwamoto, Hajime,Hasegawa, Eietsu
, p. 381 - 388 (2013/03/14)
A unique and simple preparative method for N-cyano-a-aryl-pipecolinic acid esters via base-induced Sommelet-Hauser rearrangement, the von Braun reaction, and intramolecular a-alkylation is reported. The removal of the N-cyano substituent was achieved by hydrogenation and hydride reduction.
