1353759-75-7

Upstream product

• 1353759-74-6 rac-N-[2-(3-bromo-phenyl)-2-tert-butoxycarbonylamino-propyl]-N-methyl-oxalamic acid ethyl ester 
• 887913-45-3 rac-[1-(3-bromo-phenyl)-1-methyl-2-methylamino-ethyl]-carbamic acid tert-butyl ester 
• 887913-44-2 rac-[1-(3-bromo-phenyl)-1-methyl-2-oxo-ethyl]-carbamic acid tert-butyl ester 
• 887913-69-1 rac-[1-(3-bromo-phenyl)-2-hydroxy-1-methyl-ethyl]-carbamic acid tert-butyl ester 
• 1183581-39-6 (RS)-2-amino-2-(3-bromo-phenyl)-propionic acid methyl ester 
• 1183013-69-5 (RS)-2-amino-2-(3-bromo-phenyl)-propan-1-ol 
• 953741-63-4 rac-2-amino-2-(3-bromo-phenyl)-propionitrile 
• 2142-63-4 1-(3-Bromophenyl)ethanone 

Downstream Products

• 1353759-76-8 rac-5-(3-bromo-phenyl)-3-methoxy-1,5-dimethyl-5,6-dihydro-1H-pyrazin-2-one 
• 1353759-77-9 rac-3-amino-5-(3-bromo-phenyl)-1,5-dimethyl-5,6-dihydro-1H-pyrazin-2-one 
• 1353759-86-0 rac-3'-(6-amino-2,4-dimethyl-5-oxo-2,3,4,5-tetrahydro-pyrazin-2-yl)-biphenyl-3-carbonitrile 
• 1353759-87-1 rac-3-amino-5-[3-(5-methoxy-pyridin-3-yl)-phenyl]-1,5-dimethyl-5,6-dihydro-1H-pyrazin-2-one 

Relevant academic research and scientific papers

3-AMINO-5,6-DIHYDRO-1H-PYRAZIN-2-ONE DERIVATIVES USEFUL FOR THE TREATMENT OF ALZHEIMER'S DISEASE AND OTHER FORMS OF DEMENTIA

The present invention relates to novel 3-amino-5,6-dihydro-1H-pyrazin-2-one derivatives as inhibitors of beta-secretase, also known as beta-site amyloid cleaving enzyme, BACE, BACE1, Asp2, or memapsin2. The invention is also directed to pharmaceutical com

3-AMINO-5,6-DIHYDRO-1H-PYRAZIN-2-ONE DERIVATIVES USEFUL FOR THE TREATMENT OF ALZHEIMER?S DISEASE AND OTHER FORMS OF DEMENTIA

The present invention relates to novel 3-amino-5,6-dihydro-1H-pyrazin-2-one derivatives as inhibitors of beta-secretase, also known as beta-site amyloid cleaving enzyme, BACE, BACE1, Asp2, or memapsin2. The invention is also directed to pharmaceutical com