135379-31-6

Basic information

• Product Name: Hexanedioic acid, 2-[[(1,1-dimethylethoxy)carbonyl]amino]-4-oxo-, 6-[(4-nitrophenyl)methyl] 1-(phenylmethyl) ester, (S)-
• CAS NO: 135379-31-6
• Molecular Formula: C25H28N2O9
• Molecular Weight: 500.505
• Mol File: 135379-31-6.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Hexanedioic acid, 2-[[(1,1-dimethylethoxy)carbonyl]amino]-4-oxo-, 6-[(4-nitrophenyl)methyl] 1-(phenylmethyl) ester, (S)-(CAS DataBase Reference)
• NIST Chemistry Reference: Hexanedioic acid, 2-[[(1,1-dimethylethoxy)carbonyl]amino]-4-oxo-, 6-[(4-nitrophenyl)methyl] 1-(phenylmethyl) ester, (S)-(135379-31-6)
• EPA Substance Registry System: Hexanedioic acid, 2-[[(1,1-dimethylethoxy)carbonyl]amino]-4-oxo-, 6-[(4-nitrophenyl)methyl] 1-(phenylmethyl) ester, (S)-(135379-31-6)

Safety Data

• Hazardous Substances Data: 135379-31-6(Hazardous Substances Data)

Relevant articles and documents

Antiviral peptide derivatives having a 2-oxoalkyl amino acid side chain

Disclosed herein are peptide derivatives of the formula X?--NR1 --CH(R2)--C(W1)!n --NH--CR3 (R4)--C(W2)--NR5 --CH?CH2 C(O)--Y!--C(W3)--NH--CR6 --?CR7 --(R8)--COOH!--C(W4)--NH--CR9 (R10)--Z wherein X is a terminal group, for example, alkanoyl or phenylalkanoyl radicals, R1 is hydrogen, alkyl or phenylalkyl, R2, R4 and R10 am selected from amino acid or derived amino acid residues, R3, R5, R6, R7, R8 and R9 are hydrogen or alkyl, or R7 and R8 are joined to form a cycloalkyl, W1, W2, W3 and W4 are oxo or thioxo, Y is, for example, an alkyl or a cycloalkyl, Z is a terminal group, for example, COOH or CH2 OH, and n is 0 or 1. The derivatives are useful for treating herpes infections.

Synergistic combination for treating herpes infections

Disclosed herein is a combination of an antiviral nucleoside analog and a ribonucleotide reductase inhibiting peptide derivative. The combination is useful for treating herpes infections.