135381-88-3

Upstream product

• 135381-83-8 (E)-1,1,1-Trifluoro-7-phenyl-oct-6-en-2-one 
• 122977-75-7 (Z)-1,1,1-Trifluoro-7-phenyl-oct-6-en-2-one 

Downstream Products

• 135381-89-4 (1R,2S)-2-(1-Phenyl-ethyl)-1-trifluoromethyl-cyclopentanol 

Relevant academic research and scientific papers

INTRAMOLECULAR ω-OLEFINIC-KETONE ENE-REACTION FOR THE CONSTRUCTION OF TRIFLUOROMETHYLATED FIVE-MEMBERED RING COMPOUNDS

EtAlCl2 and TiCl4-initiated cyclizations of ω-ethylenic triflluoromethylketones and β-ketoesters provide five-membered ring compounds bearing a CF3 group.

Lewis Acid-induced Ene-Cyclization of ω-Olefinic Trifluoromethyl Ketones: Access to Alicyclic Compounds bearing a CF3 Group

Several catalysts (Me2AlCl, MeAlCl2, EtAlCl2 and TiCl4) for the ene carbocyclization of olefinic trifluoromethyl ketonic compounds have been compared.Thus, five-, six-, seven- and eight-membered-ring compounds were obtained.Olefin regiochemistry and stere