1353853-39-0

Basic information

• Product Name: N-FMOC-L-phenylalanine-d8
• Synonyms: N-FMOC-L-phenylalanine-d8;SJVFAHZPLIXNDH-PLPXMBJESA-N
• CAS NO: 1353853-39-0
• Molecular Formula: C24H21NO4
• Molecular Weight: 387.42784
• Product Categories: Isotope Labelled Compounds, Pharmaceuticals, Intermediates & Fine Chemicals
• Mol File: 1353853-39-0.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• Storage Temp.: Amber Vial, -20°C Freezer, Under Inert Atmosphere
• Solubility: Chloroform
• CAS DataBase Reference: N-FMOC-L-phenylalanine-d8(CAS DataBase Reference)
• NIST Chemistry Reference: N-FMOC-L-phenylalanine-d8(1353853-39-0)
• EPA Substance Registry System: N-FMOC-L-phenylalanine-d8(1353853-39-0)

Safety Data

• Hazardous Substances Data: 1353853-39-0(Hazardous Substances Data)

Usage

Description

N-FMOC-L-phenylalanine-d8, a derivative of L-phenylalanine (P319415), is a white solid with unique chemical properties. It is characterized by the presence of deuterium (d8), which distinguishes it from its non-deuterated counterpart. N-FMOC-L-phenylalanine-d8 is commonly utilized in the synthesis of peptides and specific derivatives, such as deltorphin.

Uses

1. Used in Pharmaceutical Industry:
N-FMOC-L-phenylalanine-d8 is used as a building block for the synthesis of peptides and deltorphin derivatives, which are essential components in the development of various pharmaceutical products. The incorporation of deuterium in the compound may provide enhanced stability and altered pharmacokinetic properties to the resulting peptides.
2. Used in Research and Development:
N-FMOC-L-phenylalanine-d8 serves as a valuable tool in research and development, particularly in the study of protein structure, function, and dynamics. The presence of deuterium allows for the investigation of hydrogen/deuterium exchange, which can provide insights into protein folding, stability, and interactions with other molecules.
3. Used in Potential Inhibitor Development:
N-FMOC-L-phenylalanine-d8 is considered a potential inhibitor of the IGF-I (Insulin-like Growth Factor I) and IGF-Binding Protein-5 complex. This application is significant in the field of medicine, as modulation of the IGF axis has been implicated in the treatment of various diseases, including cancer and metabolic disorders.
4. Used in Peptide Synthesis:
In the field of peptide chemistry, N-FMOC-L-phenylalanine-d8 is employed as a key component in the preparation of peptides. The deuterated nature of the compound may offer advantages in terms of synthesis yield, purity, and the ability to study the effects of isotopic labeling on peptide behavior.