1353889-16-3

Upstream product

• 1353889-13-0 (2S,4R)-1-(tert-butyldimethylsilyloxy)-2-(triisopropylsilyloxy)undecan-4-ol 
• 1353889-14-1 (S)-8,8-diisopropyl-6-[(R)-2-(4-methoxybenzyloxy)nonyl]-2,2,3,3,9-pentamethyl-4,7-dioxa-3,8-disiladecane 
• 1353889-15-2 (2S,4R)-4-(4-methoxybenzyloxy)-2-(triisopropylsilyloxy)undecan-1-ol 
• 1353889-20-9 C₂₈H₅₀O₄Si 
• 1826-67-1 vinyl magnesium bromide 
• 1353889-09-4 methyl (S)-4-(tert-butyldimethylsilyloxy)-3-(triisopropylsilyloxy)butanoate 
• 1353889-10-7 diethyl (S)-5-(tert-butyldimethylsilyloxy)-2-oxo-4-(triisopropylsilyloxy)pentylphosphonate 

Downstream Products

• 1353889-17-4 (5S,6R)-3,3,8,8-tetraisopropyl-5-[(R)-2-(4-methoxybenzyloxy)nonyl]-2,9-dimethyl-6-vinyl-4,7-dioxa-3,8-disiladecane 

Relevant academic research and scientific papers

Stereoselective total synthesis of achaetolide from l-malic acid

A convergent total synthesis of achaetolide is described. The key steps include a Horner-Wadsworth-Emmons olefination, CBS reduction to install the stereochemistry at the C9 center, ste-reoselective vinylation to introduce the chiral center at C6, and finally- a ring-closing metathesis (RCM) reaction to construct the ten-membered lactone of the molecule. Georg Thieme Verlag Stuttgart · New York.