1354050-38-6

Basic information

• Product Name: 4-BroMo-2,6-diMethoxybenzaldehyde
• Synonyms: 4-BroMo-2,6-diMethoxybenzaldehyde
• CAS NO: 1354050-38-6
• Molecular Formula: C₉H₉BrO₃
• Molecular Weight: 245.06996
• Mol File: 1354050-38-6.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 333.6±42.0 °C(Predicted)
• Appearance: /
• Density: 1.482±0.06 g/cm3 (20 ºC 760 Torr)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 4-BroMo-2,6-diMethoxybenzaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 4-BroMo-2,6-diMethoxybenzaldehyde(1354050-38-6)
• EPA Substance Registry System: 4-BroMo-2,6-diMethoxybenzaldehyde(1354050-38-6)

Safety Data

• Hazardous Substances Data: 1354050-38-6(Hazardous Substances Data)

Usage

General Description

4-Bromo-2,6-dimethoxybenzaldehyde, also known as 40463-70-1, is a chemical compound with a molecular formula of C9H9BrO3. It is characterised by the presence of a bromine atom, two methoxy groups, and an aldehyde group attached to a benzene ring. This chemical is generally used in the field of organic synthesis, such as in the pharmaceutical industry or in research laboratories. The appearance of this compound typically ranges from crystalline solid to liquid form, and it may vary in colour from light yellow to brown. It should be handled with care due to its potential reactivity and possible health hazards.

Upstream product

• 4885-02-3 Dichloromethyl methyl ether 
• 20469-65-2 1-bromo-3,5-dimethoxybenzene 
• 67-56-1 methanol 
• 537013-51-7 4-bromo-2,6-difluorobenzaldehyde 
• 68-12-2 N,N-dimethyl-formamide 

Downstream Products

• 1399049-52-5 C₁₈H₁₅BrO₄ 
• 61203-54-1 4-bromo-2,6-dimethoxy-benzoic acid 

Relevant articles and documents

A novel selenoflavone compound as anti-obesity agent

The present invention relates to a process for producing a novel selenoflavone compound and a pharmaceutical composition for preventing or treating obesity comprising the selenoflavone compound. In the present invention, selenoflavone, especially PMSF, which has never been synthesized due to synthetic difficulties can be synthesized through palladium-catalyzed direct C-H arylation. Since the synthesized selenoflavone has an improving effect related to activation of brown adipose tissue (BAT), the selenoflavone can be used in the composition for prevention and treatment of obesity.COPYRIGHT KIPO 2018

HERBICIDALLY ACTIVE (ALKYNYL-PHENYL)-SUBSTITUTED CYCLIC DIONE COMPOUNDS AND DERIVATIVES THEREOF

The present invention relates to a compound of formula (I): wherein: X is methyl or chlorine; R1 is fluorine or bromine; R2 is ethynyl, C1-C3alkoxy, C1-C3haloalkoxy, or C1-C3alkoxy-C1-C3alkoxy-; and Q is a pyran-3,5-dione-4-yl, a thiopyran-3,5-dione-4-yl, a piperidine-3,5-dione-4-yl, a cyclopentane-1,3-dione-2-yl, a cyclohexane-1,3, 5-trione-2-yl, a cyclohexane-1,3-dione-2-yl, or a cycloheptane-1,3-dione-2-yl, or a derivative thereof (e.g. a fused such as fused bicyclic derivative, and/or a spirocyclic derivative), or an enol ketone tautomer derivative thereof, wherein Q is further defined herein; and wherein the compound of formula (I) is optionally present as an agrochemically acceptable salt thereof. Preferably, X is methyl; and/or R1 is fluorine; and/or R2 is -O-R2A, wherein R2A is methyl, ethyl, trifluoromethyl, difluoromethyl, trifluoroethyl, or -CH2CH2OCH3. These compounds are suitable for use as herbicides. The invention therefore also relates to a method of controlling weeds, especially grassy monocotyledonous weeds, in crops of useful plants, comprising applying a compound of formula (I), or a herbicidal composition comprising such a compound, to the weeds and/or to the plants and/or to the locus thereof.

7-alkyl-3-benzylcoumarins: A versatile scaffold for the development of potent and selective cannabinoid receptor agonists and antagonists

A series of 7-alkyl-3-benzylcoumarins was designed, synthesized, and tested at cannabinoid CB1 and CB2 receptors in radioligand binding and cAMP accumulation studies. 7-Alkyl-3-benzylcoumarins were found to constitute a versatile scaffold for obtaining potent CB receptor ligands with high potency at either CB1 or CB2 and a broad spectrum of efficacies. Fine-tuning of compound properties was achieved by small modifications of the substitution pattern. The most potent compounds of the present series include 5-methoxy-3-(2-methylbenzyl)-7-pentyl-2H-chromen-2-one (19a, PSB-SB-1201), a selective CB1antagonist (Ki CB 1 0.022 μM), 5-methoxy-3-(2-methoxybenzyl)-7-pentyl-2H-chromen-2- one (21a, PSB-SB-1202), a dual CB1/CB2agonist (CB 1Ki 0.032 μM, EC50 0.056 μM; CB 2Ki 0.049 μM, EC50 0.014 μM), 5-hydroxy-3-(2-hydroxybenzyl)-7-(2-methyloct-2-yl)-2H-chromen-2-one (25b, PSB-SB-1203), a dual CB1/CB2 ligand that blocks CB 1 but activates CB2 receptors (CB1Ki 0.244 μM; CB2Ki 0.210 μM, EC50 0.054 μM), and 7-(1-butylcyclopentyl)-5-hydroxy-3-(2-hydroxybenzyl)-2H-chromen-2- one (27b, PSB-SB-1204), a selective CB2 receptor agonist (CB 1Ki 1.59 μM; CB2Ki 0.068 μM, EC50 0.048 μM).