1354159-51-5Relevant academic research and scientific papers
Monitoring the DNA by ruthenium complexes of heterocyclic N,S-donor ligands and evaluation of biological activities
Karia, Parag S.,Vekariya, Pankajkumar A.,Patidar, Anshul P.,Patel, Ravi R.,Patel, Mohan N.
, p. 1903 - 1914 (2016/10/21)
Neutral N,S-donor bidentate ligands have been synthesized and characterized by NMR and IR spectroscopic techniques. The ligands have been used to synthesized ruthenium(II) complexes ([Ru(L1–L6)PPh3)2Cl2/su
DNA interaction and cytotoxic activities of square planar platinum(II) complexes with N, S-donor ligands
Patel, Mohan N.,Patel, Chintan R.,Joshi, Hardik N.,Thakor, Khyati P.
, p. 261 - 267 (2014/04/03)
The platinum(II) complexes with N, S-donor ligands have been synthesized and characterized by physicochemical methods viz. elemental, electronic, FT-IR, 1H NMR and LC-MS spectra. The binding mode and potency of the complexes with HS DNA (Herrin
Cytotoxic, DNA interaction, SOD mimic, and antimicrobial activities of square pyramidal copper(II) complexes
Patel, Mohan N.,Patel, Chintan R.,Joshi, Hardik N.
, p. 1224 - 1232 (2012/08/13)
The copper(II) complexes with NS donor ligand and ciprofloxacin were synthesized. The synthesized complexes were characterized by physicochemical parameters like elemental and thermal analysis, electronic, FT-IR, and LC-MS spectroscopy. The complexes were
Nucleic acid interaction and antibacterial behaviours of a ternary palladium(II) complexes
Patel, Mohan N.,Dosi, Promise A.,Bhatt, Bhupesh S.
experimental part, p. 508 - 514 (2012/02/05)
The bidentate ligands and Pd(II) complexes have been synthesized and characterized using elemental analysis (C, H, N), 1H NMR, 13C NMR, electronic spectra, FT-IR and FAB mass spectroscopy. The binding of palladium complexes with calf thymus DNA (CT DNA) has been explored using absorption titration, DNA melting temperature and viscosity measurements. The cleavage reaction on pUC19 DNA has been monitored by agarose gel electrophoresis. The results suggest that complexes can bind to DNA by intercalative modes and exhibit nuclease activities in which supercoil form is converted to open circular form. The antibacterial activity of ligands and complexes has been performed against three Gram(-ve) and two Gram(+ve) microorganisms and the study indicates that all the complexes show better microbial inhibition activity than ligands and palladium salt.
