1354223-67-8Relevant articles and documents
ISOQUINOLINE DERIVATIVES AS PERK INHIBITORS
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Page/Page column 119, (2018/02/17)
The invention is directed to substituted isoquinoline derivatives and uses thereof. Specifically, the invention is directed to compounds according to Formula I and the use of compounds of Formula (I) in treating disease states: (I) wherein R1,
TGF BETA RECEPTOR ANTAGONISTS
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Page/Page column 345; 346, (2017/03/08)
The invention relates generally to compounds that modulate the activity of TGFβR-1 and TGFβ R-2, pharmaceutical compositions containing said compounds and methods of treating proliferative disorders and disorders of dysregulated apoptosis, such as cancer, utilizing the compounds of the invention.