1354348-97-2Relevant academic research and scientific papers
Palladium-catalyzed direct arylation of polysubstituted benzofurans
Carrer, Amandine,Brinet, Dimitri,Florent, Jean-Claude,Rousselle, Patricia,Bertounesque, Emmanuel
, p. 1316 - 1327 (2012/03/27)
An efficient access to 2-substituted 3-arylbenzofurans through a palladium-catalyzed C3 direct arylation of 2-substituted benzofurans with aryl bromides is described. The scope and limitation of this reaction was studied. The method tolerates a variety of functional groups on the aryl halide and has been successfully extended to polysubstituted benzofurans to obtain the corresponding 3-arylbenzofurans with good to excellent yields.
