1354364-37-6

Basic information

• Product Name: 2-(2-bromo-4,5-dimethoxyphenyl)butan-2-ol
• Synonyms: 2-(2-bromo-4,5-dimethoxyphenyl)butan-2-ol
• CAS NO: 1354364-37-6
• Molecular Weight: 289.169
• Mol File: 1354364-37-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(2-bromo-4,5-dimethoxyphenyl)butan-2-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-bromo-4,5-dimethoxyphenyl)butan-2-ol(1354364-37-6)
• EPA Substance Registry System: 2-(2-bromo-4,5-dimethoxyphenyl)butan-2-ol(1354364-37-6)

Safety Data

• Hazardous Substances Data: 1354364-37-6(Hazardous Substances Data)

Upstream product

• 5293-52-7 6-bromo-3,4-dimethoxy-α-methylbenzyl alcohol 
• 5392-10-9 2-bromo-4,5-dimethoxybenzaldehyde 
• 74-96-4 ethyl bromide 
• 74746-10-4 1-(2-bromo-4,5-dimethoxyphenyl)ethanone 

Relevant articles and documents

A domino palladium-catalyzed C-C and C-O bonds formation via dual O-H bond activation: Synthesis of 6,6-dialkyl-6 H -benzo[ c ]chromenes

An efficient Pd-catalyzed domino reaction of α,α-dialkyl-(2- bromoaryl)methanols to 6,6-dialkyl-6H-benzo[c]chromenes is presented. Their formation can be explained via a five membered Pd(II)-cycle that efficiently involves a domino homocoupling with the second molecule, β-carbon cleavage, and finally intramolecular Buchwald-Hartwig cyclization. This domino process effectively involves breaking of five σ-bonds (2C-Br, 2O-H, and a C-C) and formation of two new σ-bonds (C-C and C-O). This mechanistic pathway is unprecedented and further illustrates the power of transition metal catalysis.