135450-71-4

Basic information

• Product Name: 2-Pyridinecarboxamide, 4-acetyl- (9CI)
• Synonyms: 2-Pyridinecarboxamide, 4-acetyl- (9CI)
• CAS NO: 135450-71-4
• Molecular Formula: C8H8N2O2
• Molecular Weight: 164.16132
• Product Categories: ACETYLGROUP
• Mol File: 135450-71-4.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-Pyridinecarboxamide, 4-acetyl- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Pyridinecarboxamide, 4-acetyl- (9CI)(135450-71-4)
• EPA Substance Registry System: 2-Pyridinecarboxamide, 4-acetyl- (9CI)(135450-71-4)

Safety Data

• Hazardous Substances Data: 135450-71-4(Hazardous Substances Data)

Upstream product

• 1122-54-9 methyl (4-pyridyl) ketone 
• 77287-34-4 formamide 

Relevant articles and documents

Acid-Free Silver-Catalyzed Cross-Dehydrogenative Carbamoylation of Pyridines with Formamides

Primary pyridylcarboxamides are prevalent parent structures in bioactive molecules and have the apparent advantages over N-protected derivatives as synthetic building blocks. However, no practical methods have been developed for direct synthesis of this compound class from unfunctionalized pyridines. We herein present a general, safe, concise, acid-free, and highly selective method for the C2-carbamoylation of pyridines with unprotected formamide and N-methyl formamide through the cleavage of two C-H bonds.