1354630-46-8

Basic information

• Product Name: ANTI-DYNAMIN II
• Synonyms: SHEEP ANTI-DYNAMIN 2;DYNAMIN II (AB-1) POLYCLONAL ANTIBODY;ANTI-DYNAMIN II;ANTI-DYNAMIN II, HUMAN;ANTI-DYN2;ANTI-DYNAMIN II RABBIT PAB;CMTDI1;CMTDIB
• CAS NO: 1354630-46-8
• Molecular Formula: C₁₁H₁₄O₂
• Molecular Weight: 178.22766
• Mol File: 1354630-46-8.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 305.6±22.0 °C(Predicted)
• Appearance: /
• Density: 1.046±0.06 g/cm3(Predicted)
• Storage Temp.: -20°C
• PKA: 5.19±0.40(Predicted)
• CAS DataBase Reference: ANTI-DYNAMIN II(CAS DataBase Reference)
• NIST Chemistry Reference: ANTI-DYNAMIN II(1354630-46-8)
• EPA Substance Registry System: ANTI-DYNAMIN II(1354630-46-8)

Safety Data

• Hazardous Substances Data: 1354630-46-8(Hazardous Substances Data)

Usage

Uses

Suggested starting dilutions are as follows: ICC/IF: Assay-dependent dilution, IHC-Wm: 1:100-1:500. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.

Upstream product

• 2468-55-5 5-iodopent-1-yne 
• 504-02-9 1,3-cylohexanedione 

Relevant articles and documents

TARGETED COVALENT PROBES AND INHIBITORS OF PROTEINS CONTAINING REDOX-SENSITIVE CYSTEINES

Covalent, irreversible small-molecule inhibitors that modify the sulfenyl form (i.e., sulfenic acid, RSOH and sulfenamide, RSNR'2) of therapeutically important proteins (particularly kinases and phosphatases) are disclosed, where the compositions include a compound having a substituted aryl or heterocyclic core structure that promotes binding interactions with a specific protein, and a nucleophilic reaction center (carbon, nitrogen, sulfur, or phosphorous) that is capable of forming a covalent bond with a sulfenic acid- or sulfenamide-modified cysteine residue in the protein. Methods for synthesizing these compounds are also disclosed, as well as methods of using them for determining the bioactivity of a chemical composition comprising an active compound toward a specific protein and for determining the potency of an inhibitor against a specific protein.