1354651-37-8

Basic information

• Product Name: Tert-Butyl 4-(4-Chlorophenyl)-4-Oxobutylcarbamate
• Synonyms: Tert-Butyl 4-(4-Chlorophenyl)-4-Oxobutylcarbamate
• CAS NO: 1354651-37-8
• Molecular Formula: C15H20ClNO3
• Molecular Weight: 297.7772
• Mol File: 1354651-37-8.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Tert-Butyl 4-(4-Chlorophenyl)-4-Oxobutylcarbamate(CAS DataBase Reference)
• NIST Chemistry Reference: Tert-Butyl 4-(4-Chlorophenyl)-4-Oxobutylcarbamate(1354651-37-8)
• EPA Substance Registry System: Tert-Butyl 4-(4-Chlorophenyl)-4-Oxobutylcarbamate(1354651-37-8)

Safety Data

• Hazardous Substances Data: 1354651-37-8(Hazardous Substances Data)

Upstream product

• 85909-08-6 tert-butyl 2-oxopyrrolidine-1-carboxylate 
• 873-77-8 (4-chlorphenyl)magnesium bromide 
• 24424-99-5 di-tert-butyl dicarbonate 
• 106-39-8 bromochlorobenzene 

Relevant articles and documents

Enantioselective Synthesis of 2-Substituted Pyrrolidines via Intramolecular Reductive Amination

Catalyzed by the complex generated in situ from iridium and the chiral ferrocene ligand, tert -butyl (4-oxo-4-arylbutyl)carbamate substrates were deprotected and then reductively cyclised to form 2-substituted arylpyrrolidines in a one-pot manner, in which the intramolecular reductive amination was the key step. A range of chiral 2-substituted arylpyrrolidines were synthesised in up to 98percent yield and 92percent ee.