1354657-80-9

Upstream product

• 18162-48-6 tert-butyldimethylsilyl chloride 
• 14763-60-1 4-methanesulfonyl-phenol 
• 502610-42-6 tert-butyl-(4-methanesulfonylphenoxy)dimethylsilane 
• 68453-56-5 methyl 4-(morpholinomethyl)benzoate 

Downstream Products

• 1354657-81-0 2-[4-(tert-butyldimethylsilanyloxy)benzenesulfonyl]-1-(4-morpholin-4-ylmethylphenyl)ethanol 
• 1354657-82-1 4-[(E)-2-(4-morpholin-4-ylmethylphenyl)ethenesulfonyl]phenol 
• 1354657-83-2 4-[4-[(E)-2-(4-but-2-ynyloxybenzenesulfonyl)vinyl]benzyl]morpholine 

Relevant academic research and scientific papers

N-HYDROXYFORMAMIDE DERIVATIVE AND MEDICAMENT CONTAINING SAME

A compound represented by the following general formula (I) which has ADAM17 inhibitory activity, or a salt thereof, or a solvate thereof: wherein X represents a phenylene group; Y represents a hydrogen atom, —(CH2)mR1 or the like; R1 represents —NR5COR2, —NR5SO2R2 or —NR3R4; R2 represents a C1-C6 alkyl group, an aryl group, or a C1-C6 alkoxy group; R3 and R4 represent a C1-C6 alkyl group and the like; R5 represents a hydrogen atom or a C1-C6 alkyl group or the like; m indicates an integer of from 0 to 4; and Z represents a hydrogen atom or a C1-C6 alkyl group.

COMPOSITION FOR MAINTAINING FUNCTION OF PLATELETS

A composition for maintaining a function of platelets, the composition comprising, as an active ingredient, a compound represented by the following general formula (I) or a salt thereof, or a solvate thereof: wherein X represents a phenylene group;Y represents any one of a hydrogen atom and —(CH2)mR1;wherein m represents an integer of any one of 0 to 4; andR1 is any one of —NR5COR2, —NR5SO2R2, and —NR3R4;wherein R2 represents any one of a C1 to C6 alkyl group, an aryl group, a C1 to C6 alkoxy group, and the like;R3 and R4 represent a C1 to C6 alkyl group or the like; andR5 represents any one of a hydrogen atom, a C1 to C6 alkyl group, and the like; andZ represents any one of a hydrogen atom and a C1 to C6 alkyl group.