135468-40-5Relevant academic research and scientific papers
Synthesis of (+)-Isoalantolactone and (+)-Isoalloalantolactone from (-)-Santonin
Blay, Gonzalo,Cardona, Luz,Garcia, Begona,Pedro, Jose R.,Serrano, Angel
, p. 5265 - 5272 (2007/10/02)
This paper reports on the chemical conversion of (-)-santonin into (+)-isoalantolactone and (+)-isoalloalantolactone involving functionality transfer from C6 to C8, refunctionalization of the ring A and the formation of the α-methylene-8β,12-olide moiety.
Functionality Transfer from C6 to C8 in Sesquiterpenes. Synthesis of 8-epi-Ivangustin and 8-epi-Isoivangustin from Santonin
Blay, Gonzalo,Cardona, M. Luz,Garcia, Begona,Pedro, Jose R.
, p. 6172 - 6175 (2007/10/02)
The short-range functionality transfer from C6 to C8 in eudesmane framework was reported.Santonin (1) was converted into 8-epi-ivangustin (16) and 8-epi-isoivangustin (18) via synthetic pathway involving the aforementioned functionality transfer and treatment of an intermediate diselenide 9 with m-CPBA.
