1354693-89-2Relevant academic research and scientific papers
Changing the palladium coordination to phosphinoimidazolines with a remote triazole substituent
De La Fuente, Veronica,Marcos, Rocio,Cambeiro, Xacobe C.,Castillon, Sergio,Claver, Carmen,Pericas, Miquel A.
supporting information; experimental part, p. 3255 - 3261 (2012/01/17)
Phosphinoimidazoline (PHIM) ligands bearing a triazolylmethyl substituent at the sp3 nitrogen atom in the imidazoline ring lead to highly improved enantioselectivity (up to 99% ee) in allylic substitution reactions with respect to analogous ligands with substituents lacking the triazole unit. NMR and theoretical studies support a shift in the coordination mode of the PHIM ligand to palladium, triggered by a very favourable interaction with the triazole unit. Copyright
