1354757-75-7Relevant academic research and scientific papers
A mild and efficient direct α-amination of β-dicarbonyl compounds using iodosobenzene and p-toluenesulfonamide catalyzed by perchlorate zinc hexahydrate
Yu, Jun,Liu, Shan-Shan,Cui, Jian,Hou, Xue-Sen,Zhang, Chi
supporting information; experimental part, p. 832 - 835 (2012/03/22)
A direct α-amination of β-dicarbonyl compounds has been achieved by using iodosobenzene (PhIO) as an oxidant and p-toluenesulfonamide (TsNH 2) as an aminating reagent in the presence of a catalytic amount of perchlorate zinc hexahydrate. The present amination reaction proceeds quickly at rt (30 min needed for most tested substrates) to provide the corresponding α-N-tosylamido β-dicarbonyl compounds in high to excellent yields.
