1354819-26-3

Basic information

• Product Name: 2-Hydroxy-5-(trifluoromethoxy)phenylboronic acid
• Synonyms: 2-Hydroxy-5-(trifluoromethoxy)phenylboronic acid
• CAS NO: 1354819-26-3
• Molecular Formula: C₇H₆BF₃O₄
• Molecular Weight: 221.9263496
• Mol File: 1354819-26-3.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 330.1±52.0 °C(Predicted)
• Appearance: /
• Density: 1.55±0.1 g/cm3(Predicted)
• Storage Temp.: Refrigerator, Under inert atmosphere
• Solubility: DMSO (Sparingly), Methanol (Slightly)
• PKA: 7.47±0.58(Predicted)
• CAS DataBase Reference: 2-Hydroxy-5-(trifluoromethoxy)phenylboronic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Hydroxy-5-(trifluoromethoxy)phenylboronic acid(1354819-26-3)
• EPA Substance Registry System: 2-Hydroxy-5-(trifluoromethoxy)phenylboronic acid(1354819-26-3)

Safety Data

• Hazardous Substances Data: 1354819-26-3(Hazardous Substances Data)

Usage

Uses

2-Hydroxy-5-(trifluoromethoxy)phenylboronic Acid can be used as Nav1.7 inhibitors.

Upstream product

• 290832-43-8 2-methoxy-5-trifluoromethoxybenzeneboronic acid 

Downstream Products

• 1354819-27-4 2-[3-nitro-1-(tetrahydro-2H-pyra-2-yl)-1H-pyrazol-4-yl]-4-(trifluoromethoxy)phenol 
• 1354819-28-5 tert-butyl [(5-chloro-2-fluoro-4-{2-[3-nitro-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazol-4-yl]-4-(trifluoromethoxy)phenoxy}phenyl)sulfonyl]1,3-thiazol-4-ylcarbamate 

Relevant articles and documents

CHEMICAL COMPOUNDS

The invention relates to new sulfonamide Nav1.7 inhibitors and pharmaceutically acceptable salts thereof, to their use in medicine, to compositions containing them, to processes for their preparation and to intermediates used in such processes. Nav 1.7 in