135484-74-1

Basic information

• Product Name: 3-Bromo-2-formylaniline
• Synonyms: 2-Amino-6-bromobenzaldehyde;Benzaldehyde, 2-amino-6-bromo-;3-Bromo-2-formylaniline
• CAS NO: 135484-74-1
• Molecular Formula: C₇H₆BrNO
• Molecular Weight: 200.03264
• Mol File: 135484-74-1.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 302.958 °C at 760 mmHg
• Flash Point: 137.024 °C
• Appearance: /
• Density: 1.673 g/cm³
• Refractive Index: 1.675
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: -0.72±0.10(Predicted)
• CAS DataBase Reference: 3-Bromo-2-formylaniline(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Bromo-2-formylaniline(135484-74-1)
• EPA Substance Registry System: 3-Bromo-2-formylaniline(135484-74-1)

Safety Data

• Hazardous Substances Data: 135484-74-1(Hazardous Substances Data)

Usage

Uses

2-Amino-6-bromobenzaldehyde is used in praparation of aminoquinoline compounds, and immunoconjugates as anticancer agents and uses thereof.

InChI:InChI=1/C7H6BrNO/c8-6-2-1-3-7(9)5(6)4-10/h1-4H,9H2

Upstream product

• 109513-33-9 2-Bromo-6-nitrobenzylidene(p-dimethylaminophenyl)amine N-Oxide 
• 109019-72-9 1-(2-Bromo-6-nitrobenzyl)pyridinium bromide 
• 109513-33-9 C₁₅H₁₄BrN₃O₃ 
• 55289-35-5 2-bromo-6-nitrotoluene 
• 58579-54-7 3-bromo-2-(bromomethyl)-1-nitrobenzene 
• 20357-21-5 2-bromo-6-nitrobenzaldehyde 
• 20776-48-1 2-amino-6-chlorobenzoic acid 
• 861106-92-5 (2-amino-6-bromophenyl)methanol 

Downstream Products

• 1974296-18-8 5-bromoquinoline-3-carbonitrile 
• 503321-53-7 (2'R)-cis-5-[2',5'-dihydro-4'-((tert-butyldiphenyl)silyl)oxy-2'-furanyl]-2-aminoquinazoline 

Relevant articles and documents

HETEROCYCLIC COMPOUNDS AS CBP/EP300 BROMODOMAIN INHIBITORS

The present invention provides heterocyclic compounds of formula (I), which are therapeutically useful as CBP/EP300 inhibitors. These compounds are useful in the treatment and/or prevention of diseases or disorders mediated by CBP and/or EP300 in an individual. The present invention also provides preparation of the compounds and pharmaceutical compositions comprising at least one of the compounds of formula (I) or a pharmaceutically acceptable salt, or a stereoisomer or a tautomer, an N-oxide or an ester thereof.

Acid-catalysed Cyclisation of o-Sulphonamido Ketene Dithioacetal S-Oxides: A Novel Synthesis of the Indole Ring System

Treatment of o-sulphonamido aryl ketene dithioacetal S-oxides with hydrochloric acid in the presence of hydrogen sulphide gives 2-methylthioindoles.