1354927-82-4

Basic information

• Product Name: ethyl 5-bromopicolinimidate
• Synonyms: ethyl 5-bromopicolinimidate
• CAS NO: 1354927-82-4
• Molecular Formula: C8H9BrN2O
• Molecular Weight: 229.07386
• Mol File: 1354927-82-4.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: ethyl 5-bromopicolinimidate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 5-bromopicolinimidate(1354927-82-4)
• EPA Substance Registry System: ethyl 5-bromopicolinimidate(1354927-82-4)

Safety Data

• Hazardous Substances Data: 1354927-82-4(Hazardous Substances Data)

Upstream product

• 141-52-6 sodium ethanolate 
• 97483-77-7 2-Cyano-5-bromopyridine 

Downstream Products

• 380380-64-3 5-bromo-2-(2-methyl-2H-tetrazol-5-yl)pyridine 

Relevant articles and documents

Synthesis method of tedizolid intermediate

The invention provides a synthesis method of a tedizolid intermediate. The synthesis method comprises the following steps: Step A: generating a compound (II) or acidic salt of the compound (II) through addition reaction of a cyano group in a compound (I) and alcohol; Step B: generating a compound (III) by replacing an alkoxy on the compound (II) or the acidic salt of the compound (II) with a hydrazine group or a methylhydrazine group; Step C: generating a tedizolid intermediate (IV) through reaction of the compound (III) and sodium nitrite under an acidic condition. The overall reaction formula is shown in the original specification. According to the synthesis method disclosed by the invention, the problems of easy explosion and poison of reaction reagent, difficulty in separation of a methyl-isomer by-product and so on are solved.