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Upstream product

• 1045601-63-5 3-methyl-1-(2-nitro-phenyl)-1H-indole 
• 1493-27-2 ortho-nitrofluorobenzene 
• 83-34-1 3-Methylindole 
• 870072-59-6 3-methyl-1-(2-aminophenyl)-1H-indole 
• 98-59-9 p-toluenesulfonyl chloride 

Relevant academic research and scientific papers

Iodine mediated intramolecular C2-amidative cyclization of indoles: A facile access to indole fused tetracycles

A novel and metal-free I2-mediated intramolecular C2 amidation of indoles under mild reaction conditions is developed. This methodology affords various indole fused tetracyclic compounds, such as benzo[4,5]imidazo[1,2-a]indoles by intramolecular C2 amidation of N-aryl substituted indoles. This C2 sulfonamidative cyclization also offers convenient access to indolo[2,3-b]indoles and dihydroindolo[2,3-b]quinoline from C3 aryl substituted indoles in good to excellent yields. Indolo[2,3-b]quinolines are also synthesized by the domino cyclization-detosylation-aromatization reaction sequence.

Synthesis of indolo [1,2-a ]quinoxalines via a Pd-catalyzed regioselective C - H olefination/cyclization sequence

A highly efficient approach to indolo [1,2-a]quinoxaline derivatives through a Pd-catalyzed regioselective C - H olefination/cyclization sequence has been developed. This transformation has a wide range of substrates with various functional groups, and th