135508-35-9

Upstream product

• 104-94-9 4-methoxy-aniline 
• 87727-28-4 (S)-2-tert-butyl-dimethyl-silanyloxy propanal 
• 141685-06-5 S-2-pyridyl acetoxythioacetate 
• 141781-21-7 [(S)-2-(tert-Butyl-dimethyl-silanyloxy)-prop-(E)-ylidene]-(4-methoxy-phenyl)-amine 
• 135508-31-5 [(S)-2-(tert-Butyl-dimethyl-silanyloxy)-prop-(Z)-ylidene]-(4-methoxy-phenyl)-amine 
• 13831-31-7 Acetoxyacetyl chloride 

Relevant academic research and scientific papers

Highly diastereoselective synthesis of β-lactams by addition of titanium enolates of 2-pyridyl thioesters to chiral imines

Addition of titanium enolates of 2-pyridyl thioesters to chiral imines derived from alkoxy aldehydes occurs with good diastereofacial control, and opens a simple access to important carbapenem antibiotics.

Preparation of Chiral 3-Unsubstituted β-Lactams from 3-Hydroxy β-Lactams by Using the Alkoxyketene-Imine Cycloaddition Reaction as an Approach to the Azetidinone Ring: A Formal Synthesis of the Carbapenem Antibiotic (+)-PS-5.

Formation of chiral 3-hydroxy β-lactams from the alkoxyketene-imine cycloaddition reaction followed by deoxygenation under Barton's conditions provided a simple route to optically active 3-unsubstituted β-lactams.