135508-38-2

Upstream product

• 19810-31-2 Benzyloxyacetyl chloride 
• 135508-30-4 [(S)-2-(tert-Butyl-diphenyl-silanyloxy)-prop-(Z)-ylidene]-(4-methoxy-phenyl)-amine 
• 135508-30-4 [(S)-2-(tert-Butyl-diphenyl-silanyloxy)-prop-(E)-ylidene]-(4-methoxy-phenyl)-amine 
• 104-94-9 4-methoxy-aniline 
• 87696-33-1 (S)-2-(O-tert-butyldiphenylsilyloxy)propanal 

Downstream Products

• 1059606-51-7 (2S,3S,4S)-2-Benzyloxy-4-(tert-butyl-diphenyl-silanyloxy)-3-isocyano-pentanoic acid methyl ester 
• 1054612-93-9 (2S,3S,4S)-2-Benzyloxy-4-(tert-butyl-diphenyl-silanyloxy)-3-formylamino-pentanoic acid methyl ester 
• 146860-94-8 (2S,3S,4S)-3-Amino-2-benzyloxy-4-(tert-butyl-diphenyl-silanyloxy)-pentanoic acid methyl ester 
• 146861-01-0 (2S,4S)-2-Benzyloxy-4-(tert-butyl-diphenyl-silanyloxy)-pentanoic acid methyl ester 
• 1026191-00-3 (2S,4S)-2-Benzyloxy-4-(tert-butyl-diphenyl-silanyloxy)-pentanal 
• 146860-92-6 (3S,4S)-3-Benzyloxy-4-[(S)-1-(tert-butyl-diphenyl-silanyloxy)-ethyl]-azetidin-2-one 

Relevant academic research and scientific papers

A New Entry to 1,3-Polyols, 2-Amino 1,3-Polyols, and β-(1-Hydroxyalkyl)isoserines Using Azetidinone Frameworks as Chiral Templates via Iterative Asymmetric Cycloaddition Reactions

A new entry to polyfunctional compounds based on an iterative asymmetric cycloaddition reaction of ketenes to O-protected α-hydroxy aldehyde derived imines is described for the first time.

Preparation of Chiral 3-Unsubstituted β-Lactams from 3-Hydroxy β-Lactams by Using the Alkoxyketene-Imine Cycloaddition Reaction as an Approach to the Azetidinone Ring: A Formal Synthesis of the Carbapenem Antibiotic (+)-PS-5.

Formation of chiral 3-hydroxy β-lactams from the alkoxyketene-imine cycloaddition reaction followed by deoxygenation under Barton's conditions provided a simple route to optically active 3-unsubstituted β-lactams.