13551-73-0

Basic information

• Product Name: 5-CHLORO-1,3-DIMETHYL-4-NITRO-1H-PYRAZOLE
• Synonyms: BUTTPARK 37\11-59;5-CHLORO-4-NITRO-1,3-DIMETHYLPYRAZOLE;5-CHLORO-1,3-DIMETHYL-4-NITRO-1H-PYRAZOLE;5-CHLORO-1,3-DIMETHYL-4-NITROPYRAZOLE
• CAS NO: 13551-73-0
• Molecular Formula: C₅H₆ClN₃O₂
• Molecular Weight: 175.57
• Mol File: 13551-73-0.mol
• Article Data: 6

Chemical Properties

• Melting Point: 75 °C
• Boiling Point: 275.7 °C at 760 mmHg
• Flash Point: 120.6 °C
• Appearance: /
• Density: 1.55g/cm³
• Vapor Pressure: 0.00841mmHg at 25°C
• Refractive Index: 1.625
• Storage Temp.: 2-8°C
• BRN: 149733
• CAS DataBase Reference: 5-CHLORO-1,3-DIMETHYL-4-NITRO-1H-PYRAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-CHLORO-1,3-DIMETHYL-4-NITRO-1H-PYRAZOLE(13551-73-0)
• EPA Substance Registry System: 5-CHLORO-1,3-DIMETHYL-4-NITRO-1H-PYRAZOLE(13551-73-0)

Safety Data

• Hazard Codes: Xi:Irritant
• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• Hazardous Substances Data: 13551-73-0(Hazardous Substances Data)

Usage

General Description

The chemical 5-CHLORO-1,3-DIMETHYL-4-NITRO-1H-PYRAZOLE is a pyrazole compound with a chlorine atom, two methyl groups, and a nitro group attached to the pyrazole ring. It is used in the synthesis of various pharmaceutical compounds, agrochemicals, and dyes. The compound has potential applications in the field of medicinal chemistry, as it exhibits biological activity and has been studied for its potential use in treating various diseases. Additionally, it is also used as an intermediate in the production of other organic compounds. The chemical structure and properties of 5-CHLORO-1,3-DIMETHYL-4-NITRO-1H-PYRAZOLE make it a versatile building block for the synthesis of a wide range of important compounds.

InChI:InChI=1/C5H6ClN3O2/c1-3-4(9(10)11)5(6)8(2)7-3/h1-2H3

Upstream product

• 54454-10-3 5-chloro-1,3-dimethyl-pyrazole 
• 76689-64-0 5-amino-1,3-dimethyl-4-nitro-1H-pyrazole 

Downstream Products

• 32183-13-4 1,3-dimethyl-4-nitro-1H-pyrazole-5-carbonitrile 
• 66971-55-9 5-hydrazino-1,3-dimethyl-4-nitro-1H-pyrazole 
• 1360059-52-4 6-benzyl-1,3-dimethyl-1H-pyrazolo[3,4-b]pyrazin-5(4H)- 
• 1360059-46-6 N-(1,3-dimethyl-4-nitro-1H-pyrazol-5-yl) DL-α-phenylalanine 
• 1360059-51-3 6-isobutyl-1,3-dimethyl-1H-pyrazolo[3,4-b]pyrazin-5(4H)-one 
• 104393-38-6 1,3-Dimethyl-5-(3-nitro-phenyl)-1,6-dihydro-pyrazolo[4,3-d]pyrimidin-7-one 
• 104393-37-5 1,3-dimethyl-5-(4-nitrophenyl)pyrazolo<4,3-d>pyrimidin-7-one 
• 104393-56-8 N-(5-Cyano-1,3-dimethyl-1H-pyrazol-4-yl)-4-nitro-benzamide 
• 104421-41-2 N-(5-Cyano-1,3-dimethyl-1H-pyrazol-4-yl)-3-nitro-benzamide 
• 104393-57-9 N-(5-Cyano-1,3-dimethyl-1H-pyrazol-4-yl)-3-methoxy-benzamide 
• 104393-39-7 5-(3-Methoxy-phenyl)-1,3-dimethyl-1,6-dihydro-pyrazolo[4,3-d]pyrimidin-7-one 
• 104393-43-3 5-(4-aminophenol)-1,3-dimethylpyrazolo<4,3-d>pyrimidin-7-one 
• 104393-40-0 5-(3-Amino-phenyl)-1,3-dimethyl-1,6-dihydro-pyrazolo[4,3-d]pyrimidin-7-one 
• 104393-31-9 1,3-dimethyl-5-phenylpyrazolo<4,3-d>pyrimidin-7-one 

Relevant articles and documents

TRPML MODULATORS

The present invention provides compounds, pharmaceutically acceptable compositions thereof, and methods of using the same.

Synthesis and properties of 5-chloro-4-nitropyrazoles

The nitration of 5-chloropyrazoles with a mixture of 100% nitric acid and 65% oleum or a mixture of 60% nitric acid and polyphosphoric acid gave substituted 5-chloro-4-nitropyrazoles in 45-91% yield. The nitration of 3-aryl-5-halopyrazoles was accompanied

5-Substituted derivatives of dipyrazolo[1,5-a:4',3'-e]pyrazine-6-carboxylic acids and esters

New 5-substituted derivatives of dipyrazolo[1,5-a:4',3'-e]pyrazine-6-carboxylic acid, esters and their salts have the formula STR1 R1 is hydrogen, lower alkyl or phenyl-lower alkylene; R2 and R3 each is hydrogen or lower alkyl; X is oxygen or sulfur; and R4 is hydrogen, lower alkyl, phenyl-lower alkylene or amino-lower alkylene. The new compounds are useful as anti-inflammatory agents and immunosuppressive agents.