1355169-46-8

Basic information

• Product Name: (S)-3-methyl-4-((S)-1'-phenylethylamino)butanoic acid
• Synonyms: (S)-3-methyl-4-((S)-1'-phenylethylamino)butanoic acid
• CAS NO: 1355169-46-8
• Molecular Weight: 221.299
• Mol File: 1355169-46-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (S)-3-methyl-4-((S)-1'-phenylethylamino)butanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-3-methyl-4-((S)-1'-phenylethylamino)butanoic acid(1355169-46-8)
• EPA Substance Registry System: (S)-3-methyl-4-((S)-1'-phenylethylamino)butanoic acid(1355169-46-8)

Safety Data

• Hazardous Substances Data: 1355169-46-8(Hazardous Substances Data)

Upstream product

• 40834-42-2 5-hydroxy-4-methyl-5H-furan-2-one 
• 2627-86-3 (S)-1-phenyl-ethylamine 
• 1355169-45-7 5-hydroxy-1-[1-(S)-phenylethyl]-4-methyl-1,5-dihydropyrrol-2-one 

Relevant articles and documents

Resolution of (RS)-Binol through co-crystal formation with 3-n-propyl-4-((R/S)-1′-phenylethylamino)butanoic acid

A method for the optical resolution of (RS)-Binol to obtain optically pure (S)-Binol (99% ee) through co-crystal formation with (RS)-3-n-propyl-4-((S)- 1′-phenylethylamino)butanoic acid (3RS, 1′S) and similarly optically pure (R)-Binol (99% ee) through co-crystal formation with (RS)-3-n-propyl-4- ((R)-1′-phenylethylamino)butanoic acid (3RS,1′R), in high yield is reported. The individual co-crystal of optically pure (S)-3-n-propyl-4-((S)- 1′-phenylethylamino)butanoic acid (3S,1′S) (99% ee) with (S)-Binol, and (R)-3-n-propyl-4-((S)-1′-phenylethylamino)butanoic acid (3R,1′S) (90% ee) with (S)-Binol have been analyzed by single crystal X-ray diffraction to understand hydrogen bonding in the crystal structure and the chiral recognition parameters.