135521-75-4

Basic information

• Product Name: 2-amino-4-(1,3-benzodioxol-5-yl)-9-chloro-4H,5H-thiochromeno[4,3-b]pyran-3-carbonitrile
• Synonyms: 4H,5H-[1]benzothiopyrano[4,3-b]pyran-3-carbonitrile, 2-amino-4-(1,3-benzodioxol-5-yl)-9-chloro-
• CAS NO: 135521-75-4
• Molecular Formula: C₂₀H₁₃ClN₂O₃S
• Molecular Weight: 396.8468
• Mol File: 135521-75-4.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 692.2°C at 760 mmHg
• Flash Point: 372.4°C
• Density: 1.58g/cm³
• Vapor Pressure: 5.19E-19mmHg at 25°C
• Refractive Index: 1.758
• CAS DataBase Reference: 2-amino-4-(1,3-benzodioxol-5-yl)-9-chloro-4H,5H-thiochromeno[4,3-b]pyran-3-carbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2-amino-4-(1,3-benzodioxol-5-yl)-9-chloro-4H,5H-thiochromeno[4,3-b]pyran-3-carbonitrile(135521-75-4)
• EPA Substance Registry System: 2-amino-4-(1,3-benzodioxol-5-yl)-9-chloro-4H,5H-thiochromeno[4,3-b]pyran-3-carbonitrile(135521-75-4)

Safety Data

• Hazardous Substances Data: 135521-75-4(Hazardous Substances Data)

Upstream product

• 130689-10-0 3-[1-Benzo[1,3]dioxol-5-yl-meth-(Z)-ylidene]-6-chloro-thiochroman-4-one 
• 109-77-3 malononitrile 

Relevant articles and documents

The synthesis and antifungal activity of 2-amino-4-aryl-4H,5H-benzothiopyranopyran-3-carbonitriles and 2-alkoxy-4-aryl-5H-benzothiopyranopyridine-3-carbonitriles

This paper describes the synthesis of a series of 2-amino-4-aryl-4H,5H-benzothiopyranopyran-3-carbonitriles and 2-alkoxy-4-aryl-5H-benzothiopyranopyridine-3-carbonitriles.All of these products were studied for antifungal activity and many of these compounds displayed good activity against Cryptococcus neoformans, Torulopsis glabrata, and Trichosporon cutaneum.