135522-22-4

Upstream product

• 1111-97-3 3-chloro-3-methylbut-1-yne 
• 90-02-8 salicylaldehyde 
• 19021-53-5 methyl (2-methylbut-3-yn-2-yl)carbonate 
• 89-95-2 2-methyl-benzyl alcohol 
• 6214-31-9 3-bromo-3-methylbut-1-yne 
• 115-19-5 2-methyl-but-3-yn-2-ol 
• 61570-79-4 1,1-dimethyl-2-propynyl trifluoroacetate 

Downstream Products

• 135522-27-9 2-(1',1'-dimethylallyloxy)benzaldehyde 
• 849462-04-0 2-[1-(3-bromo-isoxazol-5-yl)-1-methyl-ethoxy]-benzaldehyde 
• 1279702-96-3 C₁₉H₂₆O₅ 
• 1279702-83-8 C₁₆H₂₂O₃ 
• 135522-29-1 2-hydroxy-3-(3'methylbut-2-enyl)benzaldoxime 
• 135522-28-0 2-(1',1'-dimethylallyloxy)benzaldoxime 

Relevant academic research and scientific papers

An improved synthesis of natural product inspired chromenopyrrolizines and chromenoindolizines scaffolds: Rapid access to the diverse pyrrolizine analogs of aza-medicarpin and tetracyclic isolamellarin core through a general base and metal free strategy

An improved synthesis for easy access to the natural product inspired chromenopyrrolizine and chromenoindolizine scaffolds is delineated. The strategy involves controlled thermal activation of diverse salicylaldehyde tethered dipolarophiles having the str

N-heterocyclic carbene catalyzed intramolecular hydroacylation of activated alkynes: Synthesis of chromones

An organocatalytic intramolecular Stetter-type hydroacylation reaction between an aldehyde and an activated alkyne has been developed. This study induces salicylaldehyde-derived alkyne derivatives to assemble into a series of chromone derivatives using a

NOVEL DIAZASPIROALKANES AND THEIR USE FOR TREATMENT OF CCR8 MEDIATED DISEASES

The invention provides compounds of general formula (I) wherein A, B, p, w, x, y, and z are as defined in the specification, processes for their preparation, pharmaceutical compositions containing them and their use in therapy.

Synthesis of functionalized 1-benzoxepins by tandem ring-opening/ cyclocondensation of 3-bromoisoxazoles

A series of functionalized 1-benzoxepins were synthesized by way of a tandem ring-opening/cyclocondensation of aldehyde-containing 3-bromoisoxazoles.

Improved Synthesis of Aryl 1,1-Dimethylpropargyl Ethers

An efficient, general, and practical synthesis of aryl 1,1-dimethylpropargyl ethers has been developed.

X=Y-ZH systems as potential 1,3-dipoles. Part 31. Generation of nitrones from oximes, background and scope of the tandem 1,2-prototropy-intramolecular cycloaddition sequence

1,2-Prototropy in aryl and aliphatic oximes generates a small equilibrium concentration of the corresponding NH nitrone. Examples of a tandem 1,2-prototropy-intramolecular cycloaddition sequence involving aryl and aliphatic oximes are described and steric and electronic factors that favour or disfavour such a sequence are discussed. Deuterium labelling studies with an aliphatic oxime rule out the involvement of an enehydroxylamine in the prototropic generation of the NH nitrone.