1355249-09-0

Basic information

• Product Name: 2-(4-methoxybenzyl)-7-methyl-6,7-dihydro-2H-indazol-4(5H)-one
• Synonyms: 2-(4-methoxybenzyl)-7-methyl-6,7-dihydro-2H-indazol-4(5H)-one
• CAS NO: 1355249-09-0
• Molecular Weight: 0
• Mol File: 1355249-09-0.mol

Chemical Properties

• CAS DataBase Reference: 2-(4-methoxybenzyl)-7-methyl-6,7-dihydro-2H-indazol-4(5H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-methoxybenzyl)-7-methyl-6,7-dihydro-2H-indazol-4(5H)-one(1355249-09-0)
• EPA Substance Registry System: 2-(4-methoxybenzyl)-7-methyl-6,7-dihydro-2H-indazol-4(5H)-one(1355249-09-0)

Safety Data

• Hazardous Substances Data: 1355249-09-0(Hazardous Substances Data)

Usage

Molecular Structure

Indazolone core with a 4-methoxybenzyl group and a methyl group as substituents

Class

Organic compounds, specifically phenylmethoxybenzenes

Potential Applications

Pharmaceutical research due to possible biological activities

Research Status

Further studies and research needed to understand properties and potential uses

Upstream product

• 14203-46-4 4-methyl-cyclohexane-1,3-dione 
• 1355249-05-6 C₁₅H₁₈N₂O₄S 
• 824-94-2 p-methoxybenzyl chloride 

Relevant articles and documents

TRICYCLIC COMPOUNDS AS ALLOSTERIC MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS

The present invention describes and claims compounds of the Structural Formula (I), Structural Formula (II), or Structural Formula (III). In Formula (I), R1, R2, R3 and R3' are -H or methyl, or R3 and R3' taken together form a double bond, or R3' is -H and R2 and R3 taken together form a spiro-cyclopropyl substituent, R4 is -H or -F, and R5 is -H, methyl, -Cl or -Br. In Formula (II), R1 is -H, ethyl-, isopropyl-, cyclopropyl-, methyl- or methoxy-, R4 is -H or -F, and "Y" is: (a) -CH2-; (b) -CR6H-O-CR7R8-, wherein R6, R7, and R8 are independently -H or methyl; (c) -CR6H-N(R9)-CR7R8-, wherein R6, R7, and R8 are independently -H or methyl; (d) -CH2-C(R9)(R10)-C(R7)(R8)-, wherein R7, R8, R9 and R10 are independently -H or -methyl, or both R7 and R8 are -F, R9 and R10 are independently -H or -methyl, or both R9 and R10 are -F, or R9 and R10 taken together are (O=), which together with the carbon to which they are attached forms a carbonyl group.

TRICYCLIC COMPOUNDS AS ALLOSTERIC MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS

The present invention describes and claims compounds of the Structural Formula I, Structural Formula II, or Structural Formula III: wherein R1, R2, R3 and R3' are -H or methyl, or R3 and R3 taken together form a double bond, or R3' is -H and R2 and R3 taken together form a spiro-cyclopropyl substituent, R4 is -H or -F, and R5 is -H, methyl, -CI or -Br, Formula II wherein R1 is -H, ethyl-, isopropyl-, cyclopropyl-, methyl- or methoxy-, R4 is -H or -F, and "Y" is: (a) -CH2-; (b) -CR6H-0-CR7R8-, wherein R6, R7, and R8 are independently - H or methyl; (c) -CR6H-N(R9)-CR7R8-, wherein R6, R7, and R8 are independently -H or methyl; (d) -CH2-C(R9)(R10)-C(R7)(R8)-, wherein R7, R8, R9 and R10 are independently - H or -methyl, or both R7 and R8 are -F, R9 and R10 are independently -H or -methyl, or both R9 and R10 are -F, or R9 and R10 taken together are (0=), which together with the carbon to which they are attached forms a carbonyl group.