1355360-26-7Relevant academic research and scientific papers
Solvent effects in gold-catalysed A3-coupling reactions
Price, Gregory A.,Brisdon, Alan K.,Flower, Kevin R.,Pritchard, Robin G.,Quayle, Peter
, p. 151 - 154 (2014)
Gold-catalysed A3-reactions proceed efficiently when conducted in 2,2,2-trifluoroethanol as solvent. The rates of these reactions are accelerated considerably when conducted in a microwave reactor.
Bis-cyclometalation of fluorinated N-aryl NHCs
Harding, Duncan A. J.,Hope, Eric G.,Singh, Kuldip,Solan, Gregory A.
, p. 1518 - 1523 (2012)
The new imidazolium salts N,N′-bisfluoroarylimidazolium chloride (fluoroaryl = 4-fluorophenyl (1), 2,4-difluorophenyl (2), 2,4,6-trifluorophenyl (3)) have been prepared by the one-pot condensation of the appropriate aniline with glyoxal and formaldehyde. Reaction of the salts (1, 2) with [RuF 2(CO)3]4 and [IrF3(CO)3] in the presence of KOtBu generated the bis-cyclometalated carbene carbonyl complexes [IrCl(CO){η2-1-(C6H 4-4-F)-3-(C6H3-4-F)C3H 2N2}2] (4), [Ru(CO)2{η 2-1-(C6H4-4-F)-3-(C6H 3-4-F)C3H2N2}2] (5), and [Ru(CO)2{η2-1-(C6H3-2,4-F 2)-3-(C6H2-2,4-F2)C 3H2N2}2] (6), which have been structurally characterized.
Simple nmr predictors of catalytic hydrogenation activity for [rh(cod)cl(nhc)] complexes featuring fluorinated nhc ligands
Jamil, Mohamad Shazwan Shah,Alkaabi, Sultan,Brisdon, Alan K.
, p. 9317 - 9327 (2019/07/04)
A series of imidazolium salts precursors for N-heterocyclic carbenes (NHCs) featuring fluoroaryl substituents have been prepared along with their selenides and rhodium complexes. Tests of the catalytic activity of the [Rh(cod)Cl(NHC)] complexes in the tra
Some insights into the gold-catalysed A3-coupling reaction
Price, Gregory A.,Brisdon, Alan K.,Randall, Simon,Lewis, Edward,Whittaker, Daniel M.,Pritchard, Robin G.,Muryn, Chris A.,Flower, Kevin R.,Quayle, Peter
supporting information, p. 251 - 262 (2017/07/06)
A series of cyclometallated and functionalised NHC gold(I) and gold(III) complexes, many of which feature chiral ligands, and their application to A3-coupling reactions is presented. Gold(III) complexes were found to be particularly effective catalysts for the coupling in a range of solvents, however no asymmetric induction was obtained when using chiral gold complexes and the rate of product formation was found to be similar even when using different ligand systems. In-situ NMR analysis of these reactions indicates that decomposition of the catalyst occurs during the course of the reaction while TEM studies revealed the presence of gold nanoparticles in crude reaction mixtures. Taken together these data suggest that the gold nanoparticles, rather than the intact gold complexes, could be the catalytically active species, and if so this may have significant implications for other gold-catalysed systems.
