135544-65-9Relevant academic research and scientific papers
Efficient synthesis of phosphotyrosine building blocks using imidazolium trifluoroacetate
Gomez, Cindy,Chen, Jianyong,Wang, Shaomeng
body text, p. 6691 - 6692 (2010/01/18)
We have successfully employed imidazolium trifluoroacetate as a replacement for tetrazole for efficient synthesis of phosphotyrosine. This modification is compatible with the protecting groups commonly used in solution phase and Fmoc-solid phase peptide s
Inhibitors of signal transduction and activator of transcription 3
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Page/Page column 7, (2010/11/25)
Stat3 inhibitor compounds are disclosed, wherein the compounds are structural analogs of Ac-pTyr-Leu-Pro-Gln-Thr-NH2 and bind to the SH2 domain of Stat3 under physiological conditions to inhibit a cellular signaling activity of Stat3.
