135564-22-6

Usage

Uses

Used in Pharmaceutical Industry:
4-Bromo-3,5-difluorobenzaldehyde serves as a crucial intermediate in the synthesis of various pharmaceuticals. Its unique structure allows for the development of new drugs with specific therapeutic properties, contributing to the advancement of medicinal chemistry.
Used in Agrochemical Industry:
In the agrochemical sector, 4-Bromo-3,5-difluorobenzaldehyde is utilized as an intermediate for the production of agrochemicals. Its incorporation aids in the creation of compounds designed to protect crops and enhance agricultural productivity.
Used in Organic Synthesis:
4-Bromo-3,5-difluorobenzaldehyde is employed as a reagent in organic synthesis, particularly for the preparation of substituted benzaldehydes. Its versatility in chemical reactions makes it a valuable component in the synthesis of complex organic molecules.
Used in Fine Chemicals Industry:
4-BroMo-3,5-difluorobenzaldehyde is also used as an intermediate in the production of fine chemicals, which are high-purity chemicals used in various applications, including research, pharmaceuticals, and specialty industries.
Given its mutagenic and toxic potential, 4-Bromo-3,5-difluorobenzaldehyde requires careful handling and usage to ensure safety in all applications.

Upstream product

• 123688-59-5 2-bromo-5-cyano-1,3-difluorobenzene 
• 1415920-00-1 3,5-difluoro-4-aminobenzoic acid ethyl ester 
• 500577-99-1 4‐amino-3,5-difluorobenzoic acid 
• 110301-23-0 4-amino-3,5-difluorobenzonitrile 
• 67567-26-4 4-bromo-2,6-difluoroaniline 

Relevant academic research and scientific papers

RET INHIBITORS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF

Provided herein are a RET inhibitor, a pharmaceutical composition thereof and uses thereof. In particular, provided is a compound having Formula (I) or a stereoisomer, a geometric isomer, a tautomer, an N-oxide, a solvate, a metabolite, a pharmaceutically acceptable salt or a prodrug thereof. Provided is a pharmaceutical composition comprising the compound, and uses of the compound and pharmaceutical composition thereof for the preparation of a medicament, in particular for treatment and prevention of RET-related diseases and conditions, including cancer, irritable bowel syndrome, and/or pain associated with irritable bowel syndrome.

Bromofluoro polysubstituted benzaldehyde derivative and preparation method

The invention relates to a bromofluoro polysubstituted benzaldehyde derivative and a preparation method. The preparation method comprises the following steps: obtaining 2,6-difluoro-4-cyano phenylamine under nitrogen protection by using 2,6-difluoro-4-bro

1,3-dioxane derivative and liquid crystal compositions containing it

A 1,3-dioxane derivative and a liquid crystal composition containing it as expressed by the general formula STR1 (where R is a straight chain alkyl group of carbon number 1 to 10, A is a single bond or --CH2 CH2 -- group, n is 0 or 1, and the cyclohexane ring and 1,3-dioxane ring are respectively in trans form is disclosed.) The 1,3-dioxane derivative represented by general formula (I) has a very large dielectric anisotropy and a small birefringence. Liquid crystal compositions containing (I) can be driven at low voltage and will provide a liquid crystal display apparatus with a wide visual angle.