135583-71-0

Basic information

• Product Name: 2,2-spiropentamethylene-3-(2'-phenylsulphonylethyl)-7-methyl-3,7-diaza-4-oxabicyclo<3.3.0>octane-6,8-dione
• CAS NO: 135583-71-0
• Molecular Weight: 392.476
• Mol File: 135583-71-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2,2-spiropentamethylene-3-(2'-phenylsulphonylethyl)-7-methyl-3,7-diaza-4-oxabicyclo<3.3.0>octane-6,8-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2-spiropentamethylene-3-(2'-phenylsulphonylethyl)-7-methyl-3,7-diaza-4-oxabicyclo<3.3.0>octane-6,8-dione(135583-71-0)
• EPA Substance Registry System: 2,2-spiropentamethylene-3-(2'-phenylsulphonylethyl)-7-methyl-3,7-diaza-4-oxabicyclo<3.3.0>octane-6,8-dione(135583-71-0)

Safety Data

• Hazardous Substances Data: 135583-71-0(Hazardous Substances Data)

Upstream product

• 930-88-1 N-methylmaleimide 
• 100-64-1 cyclohexanone-oxime 
• 5535-48-8 PVS 

Relevant articles and documents

X=Y-ZH systems as potentials 1,3-dipoles. Part 321,2 generation of nitrones from oximes. Tandem Michael addition-1,3-dipolar cycloaddition reactions. Background and class 1 processes

Intermolecular Michael addition of aldoximes and ketoximes to electronegative olefins generates nitrones. The keto nitrones can be trapped in regiospecific intermolecular cycloaddition reactions giving single cycloadducts in good yield. Chemospecific 1:1:1 cycloadducts are obtained from ketoximes, monosubstituted electronegative olefins (Michael acceptor) and N-methylmaleimide (dipolarophile), whilst the chemoselectivity of the corresponding reactions with aldoximes is dependent on the oxime stereochemistry. Z-Aldoximes show high chemospecificity whilst E-aldoximes are much less chemoselective.