1356020-01-3

Basic information

• Product Name: (4S)-2-[[[(2R)-2-AMino-2-(4-hydroxyphenyl)acetyl]aMino]Methyl]-5,5-diMethyl-4-thiazolidinecarboxylic Acid (Mixture of DiastereoMers)
• Synonyms: (4S)-2-[[[(2R)-2-AMino-2-(4-hydroxyphenyl)acetyl]aMino]Methyl]-5,5-diMethyl-4-thiazolidinecarboxylic Acid (Mixture of DiastereoMers);(4S)-2-(((R)-2-aMino-2-(4-hydroxyphenyl)acetaMido)Methyl)-5,5-diMethylthiazolidine-4-carboxylic acid;AMoxicillin EP IMpurity E;AMoxicillin IMpurity E (Mixture of DiastereoMers);(4S)-2-(((R)-2-Amino-2-(4-hydroxyphenyl)acetamido)-methyl)-5,5-dimethylthiazolidine-4-carboxyl
• CAS NO: 1356020-01-3
• Molecular Formula: C15H21N3O4S
• Molecular Weight: 339.40994
• Product Categories: Aromatics;Chiral Reagents;Heterocycles;Impurities;Intermediates & Fine Chemicals;Pharmaceuticals;Sulfur & Selenium Compounds;Aromatics, Chiral Reagents, Heterocycles, Impurities, Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds
• Mol File: 1356020-01-3.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 664.4±55.0 °C(Predicted)
• Appearance: /
• Density: 1.313±0.06 g/cm3(Predicted)
• Storage Temp.: -20°C Freezer, Under inert atmosphere
• Solubility: Methanol (Slightly), Water (Slightly)
• PKA: 2.00±0.60(Predicted)
• CAS DataBase Reference: (4S)-2-[[[(2R)-2-AMino-2-(4-hydroxyphenyl)acetyl]aMino]Methyl]-5,5-diMethyl-4-thiazolidinecarboxylic Acid (Mixture of DiastereoMers)(CAS DataBase Reference)
• NIST Chemistry Reference: (4S)-2-[[[(2R)-2-AMino-2-(4-hydroxyphenyl)acetyl]aMino]Methyl]-5,5-diMethyl-4-thiazolidinecarboxylic Acid (Mixture of DiastereoMers)(1356020-01-3)
• EPA Substance Registry System: (4S)-2-[[[(2R)-2-AMino-2-(4-hydroxyphenyl)acetyl]aMino]Methyl]-5,5-diMethyl-4-thiazolidinecarboxylic Acid (Mixture of DiastereoMers)(1356020-01-3)

Safety Data

• Hazardous Substances Data: 1356020-01-3(Hazardous Substances Data)

Usage

Uses

Degradation product/impurity of Amoxicillin

Upstream product

• 26787-78-0 amoxicillin 

Relevant articles and documents

Study of the Electroreactivity of Amoxicillin on Carbon Nanotube-Supported Metal Electrodes

The electroreactivity of amoxicillin (AMX) was studied on catalysts based on platinum, palladium and ruthenium supported on carbon nanotubes (Pt/CNT, Pd/CNT, Ru/CNT) in aqueous media using cyclic voltammetry. Cyclic voltammograms show two oxidation proces

Electrochemical oxidation of amoxicillin on carbon nanotubes and carbon nanotube supported metal modified electrodes

The electrolysis of amoxicillin (AMX) was carried out on CNT, Pt/CNT and Ru/CNT modified electrodes based on Carbon Toray in 0.1 M NaOH, 0.1 M NaCl and 0.1 M Na2CO3/NaHCO3 buffer (pH 10) media with the aim of studying the significance of two factors, electrode material and pH, on the oxidative degradation and mineralization of AMX. For this purpose, the electrolysis products were identified by HPLC-MS and GC–MS, and quantified by HPLC-UV-RID and IC. The highest carbon mineralization efficiency, corresponding to 30% of the oxidized AMX, was found for Pt/CNT modified electrode in carbonate buffer medium. Regarding to the AMX conversion, the results show that the effect of pH is higher than that of the electrode material. Principal component analysis allowed to determine the experimental parameters vs. product distribution relationship and to elucidate the oxidation pathways for the studied electrodes. The results show that the hydroxylation of the aromatic ring and the nitrogen atom play an important role on the efficient degradation of AMX.