1356031-53-2Relevant academic research and scientific papers
Rhodium(II) catalyzed intermolecular double C-alkylation: A method for the synthesis of tetraindoles and indolophanes
Muthusamy, Sengodagounder,Karikalan, Thangaraju,Gunanathan, Chidambaram,Suresh, Eringathodi
experimental part, p. 1595 - 1605 (2012/03/11)
Double C-alkylation of cyclic diazoamides or bis-diazoamides with indoles or bis-indoles has been achieved to synthesize tetraindole derivatives using rhodium(II) acetate as a catalyst under mild reaction conditions with complete regioselectivity. The intermolecular double C-alkylation reaction strategy was successfully applied to synthesize indolophanes in moderate yield with excellent regiocontrol. The structure and stereochemistry of macrocycles were unequivocally confirmed with the help of single-crystal X-ray structure analyses.
