135605-97-9

Basic information

• Product Name: Silane, (1,1-dimethylethyl)dimethyl[(4-nitrophenyl)methoxy]-
• CAS NO: 135605-97-9
• Molecular Formula: C13H21NO3Si
• Molecular Weight: 267.4
• Mol File: 135605-97-9.mol
• Article Data: 20

Chemical Properties

• CAS DataBase Reference: Silane, (1,1-dimethylethyl)dimethyl[(4-nitrophenyl)methoxy]-(CAS DataBase Reference)
• NIST Chemistry Reference: Silane, (1,1-dimethylethyl)dimethyl[(4-nitrophenyl)methoxy]-(135605-97-9)
• EPA Substance Registry System: Silane, (1,1-dimethylethyl)dimethyl[(4-nitrophenyl)methoxy]-(135605-97-9)

Safety Data

• Hazardous Substances Data: 135605-97-9(Hazardous Substances Data)

Upstream product

• 29681-57-0 tert-butyldimethylsilane 
• 555-16-8 4-nitrobenzaldehdye 
• 4457-41-4 4-nitrobenzyl benzoate 
• 619-90-9 4-nitrobenzyl acetate 
• 288-32-4 1H-imidazole 
• 619-73-8 4-nitrobenzyl chloride 
• 18162-48-6 tert-butyldimethylsilyl chloride 

Downstream Products

• 619-73-8 4-nitrobenzyl chloride 
• 1426551-42-9 N-(4-(hydroxymethyl)phenyl)-3-methyl-3-(2,4,5-trimethyl-3,6-dioxocyclohexa-1,4-dien-1-yl)butanamide 
• 1380070-92-7 N-benzyl-4-((tert-butyldimethylsilyloxy)methyl)aniline 
• 229005-80-5 TAK-779 
• 229008-29-1 N-(4-hydroxymethylphenyl)-2-(4-methylphenyl)-6,7-dihydro-5H-benzocycloheptene-8-carboxamide 
• 229008-30-4 N-(4-chloromethylphenyl)-2-(4-methylphenyl)-6,7-dihydro-5H-benzocycloheptene-8-carboxamide 
• 229006-57-9 N-[4-(hydroxymethyl)phenyl]-7-phenyl-3,4-dihydronaphthalene-2-carboxamide 
• 229006-62-6 N-[4-(chloromethyl)phenyl]-7-phenyl-3,4-dihydronaphthalene-2-carboxamide 

Relevant articles and documents

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METHOD OF PREPARING (3R,5R)-7-(2-(4-FLUOROPHENYL)-5-ISOPROPYL-3-PHENYL-4-((4-HYDROXYMETHYLPHENYLAMINO)CARBONYL)-PYRROL-1-YL)-3,5-DIHYDROXY-HEPTANOIC ACID HEMI CALCIUM SALT, INTERMEDIATES USED THEREIN, AND METHOD OF PREPARING THE INTERMEDIATES

The present invention provides a method for manufacturing a (3r,5r)-7-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-((4-hydroxymethylphenylamino)carbonyl)-pyrrol-1-yl)-3,5-dihydroxy-heptanoic acid hemi-calcium salt, an intermediate thereof, and a manufacturing method thereof. According to the present invention, the manufacturing method is performed in a convergent synthesis method of individually synthesizing each main structural part of the (3r,5r)-7-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-((4-hydroxymethylphenylamino)carbonyl)-pyrrol-1-yl)-3,5-dihydroxy-heptanoic acid hemi-calcium salt and coupling the synthesized main structural parts. Accordingly, a flexible material can be easily controlled and manufacturing time can be reduced, thereby increasing productivity of a compound and yield of the final compound.COPYRIGHT KIPO 2019