1356133-53-3Relevant academic research and scientific papers
Copper-catalyzed enantioselective intramolecular alkene amination/intermolecular heck-type coupling cascade
Liwosz, Timothy W.,Chemler, Sherry R.
, p. 2020 - 2023 (2012/03/12)
Enantioselective copper-catalyzed cyclization of γ- alkenylsulfonamides and a δ-alkenylsulfonamide in the presence of a range of vinyl arenes results in variously functionalized 2-substituted chiral nitrogen heterocycles via a formal alkene C-H functionalization process. Application of this reaction to the concise synthesis of a 5-HT7 receptor antagonist is demonstrated.
