135626-19-6Relevant articles and documents
Total synthesis of (S)-(+)-melodorinol and (S)-(+)-acetylmelodorinol
Pohmakotr, Manat,Tuchinda, Patoomratana,Premkaisorn, Pornchai,Limpongpan, Attasit,Reutrakul, Vichai
, p. 795 - 802 (1999)
(S)-(+)-Melodorinol and (S)-(+)-acetylmelodorinol have been synthesized by reacting the lithiated butenolide with 2,3-O-alkylidene-D-glyceraldehyde followed by successive elimination, hydrolysis, benzoylation and acetylation reactions.
Total synthesis of acetylmelodorinol
Shen, Chien-Chang,Chou, Shiu-Ching,Chou, Cheng-Jen,Ho, Li-Kang
, p. 3141 - 3146 (1996)
An enantioselective total synthesis of bioactive melodorinol and acetylmelodorinol starting from 2,3-O-isopropylidene-D-glyceraldehyde and an alkoxyfuran is reported. Lithiation of the alkoxyfuran and subsequent reaction with the glyceraldehyde provided t
Total synthesis of both enantiomers of melodorinol. Redetermination of their absolute configurations
Lu, Xiyan,Chen, Guoying,Xia, Lijun,Guo, Guangzhong
, p. 3067 - 3072 (2007/10/03)
Both enantiomers of the natural products, melodorinol and acetylmelodorinol, have been synthesized by a palladium catalyzed enzyme coupling methodology. Their absolute configurations are redetermined.
