135634-75-2Relevant academic research and scientific papers
8-ARYL-2-AZABICYCLONONAN-7-ONES. SYNTHESIS AND RETRO-MICHAEL OPENING
Bonjoch, Josep,Quirante, Josefina,Sole, Daniel,Castells, Josep,Galceran, Montserrat,Bosch, Joan
, p. 4417 - 4428 (2007/10/02)
The synthesis of 8-aryl-2-azabicyclononan-7-ones (7) by acid cyclization of 4-(3-aryl-2-oxopropyl)-2-piperidinecarbonitriles (5) is reported.Bicyclic α-aryl-β-amino ketones 7 easily undergo a retro-Michael ring opening to give the corresponding 2-a
