1356349-85-3

Upstream product

• 79069-13-9 (S)-2-t-butoxycarbonylaminopropan-1-ol 
• 108-85-0 1-bromocyclohexane 
• 197020-60-3 (S)-tert-butyl 2-methylaziridine-1-carboxylate 

Downstream Products

• 5913-12-2 (S)-(+)-1-cyclohexyl-2-propanamine 
• 1356349-46-6 N-[2-({[(1S)-2-cyclohexyl-1-methylethyl]amino}methyl)phenyl]-8-fluoro-2,4-dioxo-1,2,3,4-tetrahydroquinazoline-6-sulfonamide 
• 1356349-87-5 (2S)-1-cyclohexyl-N-(2-nitrobenzyl)propan-2-amine 
• 1356349-89-7 tert-butyl [(2S)-1-cyclohexylpropan-2-yl](2-nitrobenzyl)carbamate 

Relevant academic research and scientific papers

HETEROCYCLIC SULFONAMIDES AS INHIBITORS OF TRANSFER RNA SYNTHETASE FOR USE AS ANTIBACTERIAL AGENTS

The present invention provides aromatic sulphonamides as tRNA synthetase inhibitors and process for their synthesis, pharmaceutical composition and method for treatment. Compounds disclosed can be used as antibacterial agents for the treatment or prevention of conditions caused by or contributed by aerobic and anaerobic Gram-positive pathogens, more particularly against bacterium, for example Staphylococcus, Enterococci and Streptococci. Compounds disclosed are used in particular for the treatment of skin and soft tissue infection, Formula (I)