1356354-05-6

Basic information

• Product Name: O-Acetyl N-Benzyloxycarbonyl Valganciclovir-d5
• Synonyms: O-Acetyl N-Benzyloxycarbonyl Valganciclovir-d5;N-[(PhenylMethoxy)carbonyl]-L-valine 3-(Acetyloxy)-2-[(2-aMino-1,6-dihydro-6-oxo-9H-purin-9-yl)Methoxy]propyl Ester-d5;[3-acetyloxy-2-[(2-amino-6-oxo-3H-purin-9-yl)methoxy]-1,1,2,3,3-pentadeuteriopropyl] (2S)-3-methyl-2-(phenylmethoxycarbonylamino)butanoate
• CAS NO: 1356354-05-6
• Molecular Formula: C24H30N6O8
• Molecular Weight: 530.5304
• Product Categories: Amino Acids & Derivatives;Bases & Related Reagents;Intermediates & Fine Chemicals;Isotope Labelled Compounds;Nucleotides;Pharmaceuticals
• Mol File: 1356354-05-6.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• Solubility: DMSO, Methanol
• CAS DataBase Reference: O-Acetyl N-Benzyloxycarbonyl Valganciclovir-d5(CAS DataBase Reference)
• NIST Chemistry Reference: O-Acetyl N-Benzyloxycarbonyl Valganciclovir-d5(1356354-05-6)
• EPA Substance Registry System: O-Acetyl N-Benzyloxycarbonyl Valganciclovir-d5(1356354-05-6)

Safety Data

• Hazardous Substances Data: 1356354-05-6(Hazardous Substances Data)

Usage

Description

O-Acetyl N-Benzyloxycarbonyl Valganciclovir-d5 is a protected, labeled derivative of Valganciclovir, which is a pro-drug of ganciclovir. It is an off-white solid with unique chemical properties that make it suitable for various applications in different industries.

Uses

Used in Pharmaceutical Industry:
O-Acetyl N-Benzyloxycarbonyl Valganciclovir-d5 is used as an intermediate compound for the synthesis of Valganciclovir. It serves as a crucial building block in the development of antiviral medications, particularly those targeting cytomegalovirus (CMV) infections.
Used in Research and Development:
In the field of research and development, O-Acetyl N-Benzyloxycarbonyl Valganciclovir-d5 is utilized as a reference material and a stable isotope-labeled compound. It aids in the investigation of the metabolic pathways, pharmacokinetics, and pharmacodynamics of Valganciclovir and its active metabolite, ganciclovir.
Used in Quality Control and Analytical Testing:
O-Acetyl N-Benzyloxycarbonyl Valganciclovir-d5 is employed as a quality control standard and an internal standard in analytical testing. It helps ensure the accuracy, precision, and reliability of Valganciclovir measurements in various samples, such as pharmaceutical formulations, biological fluids, and environmental samples.
Used in Drug Synthesis and Process Optimization:
O-Acetyl N-Benzyloxycarbonyl Valganciclovir-d5 is used as a key intermediate in the synthesis of Valganciclovir and its analogs. It plays a vital role in optimizing the chemical processes and improving the overall yield and purity of the final product.
Used in Radiolabeling Studies:
O-Acetyl N-Benzyloxycarbonyl Valganciclovir-d5 can be used in radiolabeling studies to investigate the biodistribution, metabolism, and pharmacological effects of Valganciclovir and its metabolites in preclinical and clinical settings.