1356407-65-2Relevant academic research and scientific papers
Oxidative Annulation of Arenecarboxylic and Acrylic Acids with Alkynes under Ambient Conditions Catalyzed by an Electron-Deficient Rhodium(III) Complex
Kudo, Eiji,Shibata, Yu,Yamazaki, Mutsumi,Masutomi, Koji,Miyauchi, Yuta,Fukui, Miho,Sugiyama, Haruki,Uekusa, Hidehiro,Satoh, Tetsuya,Miura, Masahiro,Tanaka, Ken
supporting information, p. 14190 - 14194 (2016/09/23)
It has been established that an electron-deficient CpErhodium(III) complex catalyzes the oxidative [4+2] annulation of substituted arenecarboxylic and acrylic acids with alkynes under ambient conditions (at RT–40 °C, under air) without using excess amounts of substrates to produce the corresponding substituted isocoumarins and α-pyrones in high yields. Minor modification of reaction conditions depending on the coordination ability of alkynes realized the high efficiency.
Rhodium(III)-Catalyzed C-H Activation/Alkyne Annulation by Weak Coordination of Peresters with O-O Bond as an Internal Oxidant
Mo, Jiayu,Wang, Lianhui,Cui, Xiuling
supporting information, p. 4960 - 4963 (2015/11/03)
A redox-economic strategy has been developed, involved in an efficient Rh(III)-catalyzed oxidative C-H activation and alkyne annulation with perester as the oxidizing directing group. In this process, the cleavage of an oxidizing O-O bond as an internal oxidant is described for the first time. This reaction could be carried out under mild conditions and exhibits excellent regioselectivity and wide functional groups tolerance.
Rhodium(III)-catalyzed, C-H activated annulation to form isocoumarins and α-pyrones using the O-N bond as an internal oxidant
Li, Xing Guang,Liu, Kai,Zou, Gang,Liu, Pei Nian
, p. 1496 - 1500 (2014/06/09)
A mild, efficient and regioselective C-H activation-based intermolecular redox-neutral annulation of O-benzoylhydroxylamines and internal alkynes has been achieved. The protocol employs an O-N bond as the internal oxidant and leads to isocoumarins and α-pyrones.
Versatile synthesis of isocoumarins and α-pyrones by Ruthenium-catalyzed oxidative C - H/O - H bond cleavages
Ackermann, Lutz,Pospech, Jola,Graczyk, Karolina,Rauch, Karsten
supporting information; experimental part, p. 930 - 933 (2012/03/26)
An inexpensive cationic ruthenium(II) catalyst enabled the expedient synthesis of isocoumarins through oxidative annulations of alkynes by benzoic acids. This C - H/O - H bond functionalization process also proved applicable to the preparation of α-pyrones and was shown to proceed by rate-limiting C - H bond ruthenation.
