1356475-80-3Relevant academic research and scientific papers
Primaquine-thiazolidinones block malaria transmission and development of the liver exoerythrocytic forms
Aguiar, Anna Caroline C.,Figueiredo, Flávio Jr. B.,Neuenfeldt, Patrícia D.,Katsuragawa, Tony H.,Drawanz, Bruna B.,Cunico, Wilson,Sinnis, Photini,Zavala, Fidel,Krettli, Antoniana U.
, (2017/03/20)
Background: Primaquine is an anti-malarial used to prevent Plasmodium vivax relapses and malaria transmission. However, PQ metabolites cause haemolysis in patients deficient in the enzyme glucose-6-phosphate dehydrogenase (G6PD). Fifteen PQ-thiazolidinone
Multicomponent synthesis of new primaquine thiazolidinone derivatives
Neuenfeldt, Patricia D.,Drawanz, Bruna B.,Aguiar, Anna Caroline C.,Figueiredojr. Jr., Flavio,Krettli, Antoniana U.,Cunico, Wilson
experimental part, p. 3866 - 3870 (2012/01/11)
Primaquine thiazolidinone derivatives, potentially useful as antimalarial agents, were synthesized in good yields by multicomponent reactions of primaquine diphosphate, mercaptoacetic acid, and an optionally substituted benzaldehyde or cyclohexanone for t
