1356485-35-2Relevant academic research and scientific papers
A Facile one-pot three-component synthesis of 5-(trifluoromethyl)-4,7- dihydro-[1,2,4]-triazolo[1,5-a]pyrimidine derivatives in ionic liquid
Li, Tuanjie,Yao, Changsheng,Lei, Song,Yu, Chenxia,Tu, Shujiang
, p. 2427 - 2432 (2011)
An efficient one-pot synthesis of 5-(trifluoromethyl)-4,7-dihydro-7-aryl- [1,2,4]triazolo[1,5-a]pyrimidine derivatives was performed via the reaction of aryl aldehyde, 3-amino-1,2,4-triazole and ethyl 4,4,4-trifluoro-3-oxobutanoate or 4,4,4-trifluoro-1-phenylbutane-1,3-dione in ionic liquid. This method has the advantages of short synthetic route, operational simplicities, mild reaction conditions, high yields and eco-friendliness.
