1356485-76-1Relevant academic research and scientific papers
Taming the friedel-crafts reaction: Organocatalytic approach to optically active 2,3-dihydrobenzofurans
Albrecht, Lukasz,Ransborg, Lars Krogager,Lauridsen, Vibeke,Overgaard, Mette,Zweifel, Theo,Jorgensen, Karl Anker
, p. 12496 - 12500 (2011)
Fine-tuning: Three types of optically active trans-2,3-disubstituted-2,3- dihydrobenzofurans having three contiguous stereogenic centers can be efficiently accessed by one-pot reaction cascades (see scheme; TMS=trimethylsilyl). High substitution diversity of the final products can be achieved from the same common precursors by fine-tuning of their reactivity through simple structural modifications. Copyright
