1356491-06-9Relevant academic research and scientific papers
A concise one-pot approach to the synthesis of 4-(1 H-indol-3-yl)quinolines
Arcadi, Antonio,Chiarini, Marco,Marinelli, Fabio,Picchini, Silvia
experimental part, p. 4084 - 4090 (2012/01/05)
An operationally simple procedure, involving conjugate addition of NaI to β-(2-aminophenyl)-α,β-ynones/cyclization/Pd-catalyzed reaction with 2-alkynyl-trifluoroacetanilides, afforded 4-(1H-indol-3-yl)quinolines. The whole process was carried out in the same flask, without any intermediate work-up and using ethanol as solvent. Georg Thieme Verlag Stuttgart · New York.
