1356541-98-4Relevant academic research and scientific papers
Tunable and Diastereoselective Br?nsted Acid Catalyzed Synthesis of β-Enaminones
Kang, Ye-Won,Cho, Yu Jin,Han, Seung Jin,Jang, Hye-Young
supporting information, p. 272 - 275 (2016/02/03)
The Br?nsted acid catalyzed Meyer-Schuster reaction of hemiaminals was studied for the stereoselective synthesis of β-enaminones. Hemiaminals were formed from propargyl aldehydes (or the oxidation of propargyl alcohols) and amines in the presence of Br?ns
Highly regioselective synthesis of cis-β-enaminones by 1,4-addition of propiolaldehydes
Shi, Wenjuan,Sun, Shaofa,Wu, Minghu,Catano, Bryant,Li, Wan,Wang, Jian,Guo, Haibing,Xing, Yalan
supporting information, p. 468 - 471 (2015/04/27)
A convenient one-pot strategy for the regioselective synthesis of cis-β-enaminones has been developed via the condensation of propiolaldehydes and amines in EtOH. This process has opened a new synthetic route to enamines in good yield. A possible reaction mechanism involving a Michael addition/enol tautomerization via a six-membered ring transition state is proposed.
Highly stereoselective synthesis of cis-β-enaminones mediated by diethyl azodicarboxylate
Xu, Xiaoliang,Du, Ping,Cheng, Dongping,Wang, Hong,Li, Xiaonian
supporting information; experimental part, p. 1811 - 1813 (2012/02/16)
Promoted by diethyl azodicarboxylate, a novel and highly stereoselective synthesis of cis-β-enaminones via oxidative dehydrogenation and hydration of the substituted propargylamines was realized. The possible mechanism was also proposed.
