135663-76-2

Upstream product

• 126461-69-6 1,5-anhydro-3-O-benzyl-6-O-tert-butyldimetylsilyl-2-deoxy-D-arabino-hex-1-enopyranose 
• 4098-06-0 triacetyl-D-galactal 
• 135758-74-6 (E)-(4R,6S,9R)-1-Benzenesulfonyl-6-benzyloxy-10-(tert-butyl-diphenyl-silanyloxy)-3,9-dimethyl-dec-2-en-4-ol 
• 135663-46-6 Methanesulfonic acid (2R,3S,4R,6S)-4-benzyloxy-2-(tert-butyl-dimethyl-silanyloxymethyl)-6-methoxy-tetrahydro-pyran-3-yl ester 
• 135663-46-6 Methanesulfonic acid (2R,3R,4R)-4-benzyloxy-2-(tert-butyl-dimethyl-silanyloxymethyl)-6-methoxy-tetrahydro-pyran-3-yl ester 
• 135663-56-8 Methanesulfonic acid (1S,2R)-2-benzyloxy-1-((R)-1,2-dihydroxy-ethyl)-3-[1,3]dithian-2-yl-propyl ester 
• 135720-60-4 Methanesulfonic acid (1R,2R)-2-benzyloxy-1-((R)-1,2-dihydroxy-ethyl)-3-[1,3]dithian-2-yl-propyl ester 
• 135663-47-7 Methanesulfonic acid (1S,2R)-2-benzyloxy-3-[1,3]dithian-2-yl-1-formyl-propyl ester 
• 135758-73-5 Methanesulfonic acid (1R,2R)-2-benzyloxy-3-[1,3]dithian-2-yl-1-formyl-propyl ester 
• 20701-47-7 Acetic acid (2R,3S,4S,5S)-4-acetoxy-2-acetoxymethyl-5-iodo-6-methoxy-tetrahydro-pyran-3-yl ester 
• 1043893-21-5 Acetic acid (2R,3R,4R)-4-acetoxy-2-acetoxymethyl-6-methoxy-tetrahydro-pyran-3-yl ester 
• 135663-52-4 (2R,3R,4R)-4-Benzyloxy-2-(tert-butyl-dimethyl-silanyloxymethyl)-6-methoxy-tetrahydro-pyran-3-ol 
• 122795-03-3 (2R,3R,4R)-2-(tert-Butyl-dimethyl-silanyloxymethyl)-6-methoxy-tetrahydro-pyran-3,4-diol 
• 135663-63-7 ((2R,5S)-5-Benzyloxy-6-[1,3]dithian-2-yl-2-methyl-hexyloxy)-tert-butyl-diphenyl-silane 

Downstream Products

• 135663-78-4 ((E)-(2R,5S,7S)-10-Benzenesulfonyl-5-benzyloxy-7-methoxy-2,8-dimethyl-dec-8-enyloxy)-tert-butyl-diphenyl-silane 
• 135663-82-0 (5E,7E,9E)-(2R,4S,11S,13S,16R)-13-Benzyloxy-17-(tert-butyl-diphenyl-silanyloxy)-11-methoxy-2,4,10,16-tetramethyl-heptadeca-5,7,9-trien-1-ol 
• 135663-79-5 ((8E,10E,12E)-(2R,5S,7S,14S,16R)-5-Benzyloxy-16-[1,3]dithian-2-yl-7-methoxy-2,8,14-trimethyl-heptadeca-8,10,12-trienyloxy)-tert-butyl-diphenyl-silane 
• 135663-85-3 (5E,7Z,9E)-(2R,4S,11S,13S,16R)-8-Benzenesulfonyl-13-benzyloxy-17-(tert-butyl-diphenyl-silanyloxy)-11-methoxy-2,4,10,16-tetramethyl-heptadeca-5,7,9-trienal 
• 135663-84-2 ((8E,10Z,12E)-(2R,5S,7S,14S,16R)-10-Benzenesulfonyl-5-benzyloxy-16-[1,3]dithian-2-yl-7-methoxy-2,8,14-trimethyl-heptadeca-8,10,12-trienyloxy)-tert-butyl-diphenyl-silane 
• 135663-81-9 Acetic acid (E)-(5S,7S,10R)-2-benzenesulfonyl-7-benzyloxy-11-(tert-butyl-diphenyl-silanyloxy)-1-((E)-(3S,5R)-3,5-dimethyl-6-oxo-hex-1-enyl)-5-methoxy-4,10-dimethyl-undec-3-enyl ester 
• 135663-83-1 Acetic acid (E)-(5S,7S,10R)-2-benzenesulfonyl-7-benzyloxy-11-(tert-butyl-diphenyl-silanyloxy)-1-((E)-(3S,5R)-5-[1,3]dithian-2-yl-3-methyl-hex-1-enyl)-5-methoxy-4,10-dimethyl-undec-3-enyl ester 
• 135663-86-4 (5E,7E,9E)-(2S,4S,11S,13S,16R)-13-Benzyloxy-17-(tert-butyl-diphenyl-silanyloxy)-11-methoxy-2,4,10,16-tetramethyl-heptadeca-5,7,9-trienal 
• 135663-86-4 (5E,7E,9E)-(2R,4S,11S,13S,16R)-13-Benzyloxy-17-(tert-butyl-diphenyl-silanyloxy)-11-methoxy-2,4,10,16-tetramethyl-heptadeca-5,7,9-trienal 

Relevant academic research and scientific papers

Application of the Ibuka-Yamamoto Reaction to a Problem in Stereochemical Communication: A Strategy for the Stereospecific Synthesis and Stabilization of the Triene Substructure of Rapamycin through Sulfone Substitution

The aldehydes 49 and 55 corresponding to carbons 13-30 in a projected total synthesis of rapamycin have been synthesized.The LACDAC technology was used to elaborate dithiane enal 5.The aldehyde 4 was synthesized from D-(+)-glucose.A critical element of th